NF Lactose

Foremost Farms USA. Technical literature NF Lactose 310, NF Lactose 312, NF Lactose 313, 2004. 

FlowLac 100 Lactopress Spray-Dried NF Lactose-316 Fast Flo NF Lactose-315 Pharmatose DCL 11 Pharmatose DCL 14 Super-Tab Spray-Dried. 

Brittle fracture index 0.1671 for NF Lactose-315 (compression pressure 54.90 MPa) ... 

Whey concentration, both of whole whey and ultrafiltration permeate, is practiced successfully, but the solubility of lactose hmits the practical concentration of whey to about 20 percent total sohds, about a 4x concentration fac tor. (Membranes do not tolerate sohds forming on their surface.) Nanofiltration is used to soften water and clean up streams where complete removal of monovalent ions is either unnecessary or undesirable. Because of the ionic character of most NF membranes, they reject polyvalent ions much more readily than monovalent ions. NF is used to treat salt whey, the whey expressed after NaCl is added to curd. Nanofiltration permits the NaCl to permeate while retaining the other whey components, which may then be blended with ordinaiy whey. NF is also used to deacidify whey produced by the addition of HCl to milk in the production of casein. 

Lactose Direct Tableting NF, Ph Eur, JP, BP Anhydrous, NF Quest International... 

Whiteman M, Yarwood RJ. Variations in lactose NF from two different sources and their influence on tablet properties. Drug Dev Ind Pharma 1990 16(11) 1815 1827. 

Lactose monohydrate, corn starch, modified starch, povidone 25000, magnesium stearate, HPMC, Macrogol 6000, talc, titanium dioxide, ferric oxide pigment, yellow NF... 

Pharmatose DCL 22 Lactose anhydrous NF DT Lactose anhydrous NF DT High Velocity DMV International Kerry Bio-Sciences Kerry Bio-Sciences 0.67 g/mL 15% <45 pm, 35% <150 pm, 75% <250 pm 35-50% >180 pm 40-60% >180 pm, 15-35% >250 pm Good for low and high drug dose Good compactibility, low friability, good dissolution, improved moisture stability Faster flow and improved tablet uniformity... 

Kerry Bio-Sciences (Sheffield Products). 2006. Technical Literature Lactose monohydrate NF 180 MS HV, lactose anhydrous NF DT, lactose anhydrous NF DT high velocity. 

Standard Solution Transfer about 2 g of NF-grade anhydrous lactose, accurately weighed, to a 100-mL volumetric flask, add 10 mL of Fructose Internal Standard Solution, and dilute to volume with water. Prepare fresh daily. 

Application of NF in the simultaneous demineralization and concentration of whey, concentration of lactose from the permeate of the UF whey, and the purification of membrane cleaning solutions. 

Anhydrous Lactose NF 60M- Anhydrous Lactose NF Direct Tableting Lactopress Anhydrous lactosum lattioso milk sugar Pharmatose DCL 21 Pharmatose DCL 22 saccharum lactis Super-Tab Anhydrous. 

Water content <0.5% loss on drying and <1.0% water content for Anhydrous Lactose NF Direct Tableting and Anhydrous Lactose NF 60M 0.2% loss on drying and 0.5% water content for Pharmatose DCL 21 (typical) 0.2% loss on drying and 0.2% water content for Pharmatose DCL 22 (typical) 0.15% loss on drying for Super-Tab Anhydrous (typical). 

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