Nevus comedonicus

Application of hydrophilic ointment was permitted in those patients who required a topical lubricant. Hydroxyzine hydrochloride was given to a few patients for control of pruritus. White petrolatum was used for the cheilitis resulting from treatment with 13-cis retinoic acid. Oral erythromycin or cloxacillin was necessary to control the recurrent cutaneous infections of 2 patients with Darier s disease and the one with nevus comedonicus. 

The patients with X-linked ichthyosis, Netherton s syndrome, nevus comedonicus, or psoriasis either worsened or failed to improve. 

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