Neurotransmitters, role

Picrotoxin has been instmmental in estabUshing an inhibitory neurotransmitter role for the amino acid, gamma-aminobutyric acid (GABA), quantitatively the most important inhibitory neurotransmitter in the mammalian CNS. Whereas glycine is predominately localized in the spinal cord, GABA... 

Dopamine (3 4 dihydroxyphenylethylamine), like noradrenaline and adrenaline, is a eateeholamine and in addition to its independent neurotransmitter role in the CNS it is a preeursor to noradrenaline (NA) in all central and peripheral noradrenegic neurons. 

Glycine is the simplest of all amino acids. It is involved in many metabolic pathways, is an essential component of proteins, and is found throughout the brain. A neurotransmitter role for glycine was first identified in the spinal cord, where it was found to be differentially distributed between dorsal and ventral regions and shown to cause hyperpolarisation of motoneurons (Werman et al. 1967). This inhibitory action of glycine is distinct from its... 

Thus the neurotransmitter role of ATP is well established in the periphary and also in sensory systems but its importance in the CNS remains to be elucidated (see Burnstock 1996). That requires the development of more specific antagonists and methods of mapping its location. The strong linkage of its P2x receptors to calcium currents may also provide a role for ATP in more long-term effects such as plasticity and neuronal development and death. 

Hj, Hj, and Hj receptors are present in the CNS. Tricyclic antidepressant drugs seem to interact with histamine receptors in the CNS. Histamine receptor subtypes in the CNS and the central neurotransmitter role of histamine have been the subject of many recent investigations. Currently there are three central histamine receptors ... 

The exact neurotransmitter role of histamine in the CNS remains an enigma. However, regulation of arousal and appetite by histamine has long been suggested by... 

ANGIOTENSIN RECEPTOR AGONISTS are a family of potent agents with notable actions on the cardiovascular system and electrolyte balance, but have many other possible pathophysiological functions, including a putative central neurotransmitter role. 

DOPAMINE RECEPTOR AGONISTS act to stimulate dopamine receptors, and these have a major neurotransmitter role in the CNS. Dopamine is also a precursor in the formation of the catecholamine monoamine neurotransmitter noradrenaline and the hormone adrenaline. 

IS GLUTAMATE IMMUNOLABELING EVIDENCE OF A NEUROTRANSMITTER ROLE FOR GLUTAMATE ... 

Collins, G.C.S. (1979) Evidence of a neurotransmitter role of aspartate and gamma-aminobutyric acid in the rat olfactory cortex. J. Physiol, 291, 51-60. 

Which one of the following chemicals does not satisfy the criteria for a neurotransmitter role in the CNS ... 

Is a Neurotransmitter Role the Main Function of Taurine in the Central Nervous System ... 

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