Neuroendocrine prostatic neoplasms

As in other organs, the spectrum of neuroendocrine neoplasms in the prostate include carcinoid tumors, small cell carcinoma, and large cell neuroendocrine carcinoma as defined in the lung by Travis and colleagues. 

As mentioned previously, octreotide is an analog of the hormone somatostatin (Fig. 5) and has been used for both diagnostic and therapeutic purposes. Much of the work has centered on neuroendocrine tumors because of their high somatostatin receptor concentrations however, other common types of neoplasms, such as gliomas, lymphomas, breast and prostate cancers, may also contain considerable numbers of somatostatin receptors [41], Indium-111 has been labeled to DTPA-conjugated octreotide and administered to patients for scintigraphic imaging of various... 

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