Needleless injection

Other delivery systems are transdermal patches, metered dose inhalers, nasal sprays, implantable devices, and needle-free injections. A description of needleless injection is given in Exhibit 5.16. 

Needleless injections are new devices to bypass this problem. Drugs in powder or liquid form can be injected into the subcutaneous layer in the following ways ... 

Needleless injection is ideal for frequent injections, as in the cases of insulin and growth hormone, which are administered routinely. 

Needleless injections—Liquid or powdered drugs propelled with pressure through the skin. 

Problems facing needleless injection systems include the high developmental cost of both the device and dosage form and the inability, unlike some of the other techniques described previously, to programme or control drug delivery in order to compensate for inter-subject differences in skin permeability. In addition, the... 

Needleless injections are new devices to bypass this problem. Drugs in powder or liquid form can be injected into the subcutaneous layer in the following ways Propelled by a jet stream of compressed air Fired as pallets similar to that of bullets from rifles Electroporation (a temporary application of direct current, which disturbs the skin surface and allows penetration of the drug molecules). 

Drug delivery is a growing area of healthcare technology. Needleless injection techniques and inhalation are specific modes of delivery that are fueling this growth, driven largely by elevated requirements for patient comfort. As with blood handling applications, biocompatibility and sterilizability are key requirements. However, impact and wear resistance are also important. Some of the blends used in these applications include PC/PBT and PC/ABS. 

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