Navigating the Solid Form Landscape with Structural Informatics

NAVIGATING THE SOLID FORM LANDSCAPE WITH STRUCTURAL INFORMATICS 

Peter T. A. Galek Etna Pidcock, Peter A. Wood Neil Feeder, and Frank H. Allen  

There are several well-documented cases of the conversion of existing marketed drugs to previously unknown polymorphs, for example ritonavir [2] and rotigotine [3], with serious medical, social and financial consequences. It is therefore crucial for drug development scientists to understand, as far as possible, the solid form landscape. 

Computational Pharmaceutical Solid State Chemistry, First Edition. Edited by Yuriy A. Abramov. 2016 John Wiley Sons, Inc. Published 2016 by John Wiley Sons, Inc. 

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