Nausea goals

The primary goal of treatment is to relieve the symptoms of nausea and vomiting, which should increase the patient s quality of life. Drug therapy for nausea and vomiting should be safe, effective, and economical. 

The goals of treatment for acute pancreatitis include (1) resolution of nausea, vomiting, abdominal pain, and fever (2) ability to tolerate oral intake (3) normalization of serum amylase, lipase, and white blood cell count and (4) resolution of abscess, pseudocyst, or fluid collection as measured by CT scan. 

The treatment goals for withdrawal from ethanol, cocaine/ amphetamines, and opioids include (1) a determination if pharmacologic treatment of withdrawal symptoms is necessary, (2) management of medical manifestations of withdrawal such as hypertension, seizures, arthralgias, and nausea, and (3) referral to the appropriate program for substance abuse treatment. 

The overall goal of antiemetic therapy is to prevent or eliminate nausea ... 

G. Other applications Limited data show some beneficial effects of leuprolide in the treatment of breast cancer. According to Micromedex, there is good documentation that leuprolide is effective for bowel pain and nausea associated with irritable bowel syndrome. Leuprolide has been used for controlled ovarian hyperstimulation to enhance the in vitro fertilization-embryo transfer procedure. In endometriosis, the goal of treatment is pain relief and reduction of endometriotic lesions. In children with central precocious puberty, stimulated and basal gonadotropins are reduced to prepubertal levels. Testosterone and estradiol are reduced to prepubertal levels in males and females, respectively. 

The primary goal with chemotherapy-induced nausea and vomiting (CINV) is to prevent nausea and/or vomiting. 

Nausea and vomiting that occurs within 24 hours of chemotherapy administration is defined as acute, whereas when it starts more than 24 hours after chemotherapy administration, it is defined as delayed. The primary goal with CINV is to prevent nausea and/or vomiting optimal control of acute nausea and vomiting positively impacts the incidence and control of delayed and anticipatory nausea and vomiting. Clinical practice guidelines for the use of antiemetics in CINV have been published. Despite the availability of nationally recommended guidelines, individual practice varies from one institution to the next. Product availability and recommended doses are institution-specific and may vary considerably from the doses listed in Table 35-5. 

---