Nausea General

Inhalation of mercury vapor may produce a metal fume fever-like syndrome, including chills, nausea, general malaise, tighmess in the chest, and respiratory symptoms. High concentrations cause corrosive bronchitis and interstitial pneumonitis. In the most severe cases, the patient will succumb because of respiratory insufficiency. In one episode involving four workers, it was estimated that mercurial pneumonitis resulted from exposure for several hours to concentrations ranging between 1 and 3mg/m. ... 

Hyponatremia is defined as a decreased plasma Na concentration (<136 mmoI/L). Hyponatremia typically manifests itself clinically as nausea, generalized weakness, and mental confusion at values <120 mmol/L, ocular palsy at <110 mmol/L, and severe mental impairment between 90 and 105 mmol/L. The central nervous system (CNS) symptoms are primarily due to movement of H2O into cells to maintain osmotic balance and thus sweUing of CNS cells. The rapidity of the development of hyponatremia influences... 

Corrosive - irritation to respiratory tract. May form HCl in limgs. Respiratory choking, dizziness, nausea, general weakness. Pulmonary edema may develop after latency period. Dyspnea, cyanosis, rapid pnlse. 

Methanol is not classified as carcinogenic, but can be acutely toxic if ingested 100—250 mL may be fatal or result in blindness. The principal physiological effect is acidosis resulting from oxidation of methanol to formic acid. Methanol is a general irritant to the skin and mucous membranes. Prolonged skin contact with methanol vapor or Hquid can cause dermatitis. Methanol vapor can cause eye and respiratory tract irritation, nausea, headaches, and dizziness. 

A Chinese traditional herbal treatment for malaria obtained from the roots of Dichroafebrifuga is called Ch ang Shan and was investigated in the 1940s. Febrifugine (80), the alkaloid responsible for its activity, was isolated and found to be considerably more active than quinine in experimental infections. Unfortunately, the dmg caused nausea and vomiting in humans. Synthesized analogues were generally less effective than the parent. 

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