Nasal decongestants antihistamine combination

Ibuprofen, pseudoephedrine and chlorpheniramine are the drag substances have an effect as antihistaminic, nasal decongestant and antiinflammatory, respectively. The combination of these drags, is effective in cold, sinus and flu symptoms and used for upper respiratory infections. Nipagen (methylparaben) is widely used as... 

Triprolidine is an antihistamine. Phenylpropranolamine, pseudoephedrine, phenylephrine and oxymetazoline are nasal decongestants. Nasal decongestants administered systemically are often available in combination with an antihistamine. 

Rynatan pediatric suspension is an antihistamine/nasal decongestant combination available for oral administration as a suspension. Each 5 mL (one teaspoonful) of the slate-purple-colored, natural strawberry-artificial currant-flavored suspension contains phenylephrine tannate 5 mg, chlorpheniramine tannate 4.5 mg, benzoic... 

Because of their limited effects on allergic symptoms, decongestants often are used in combination with antihistamines.8 Many antihistamines are available in fixed-dose combinations with pseudoephedrine, which enhances the reduction in nasal congestion and allows for the patient convenience of one tablet. Optimally, therapy should be initiated with an antihistamine alone, adding the adrenergic agent only if nasal congestion does not resolve with antihistamine monotherapy. Use of separate antihistamine and pseudoephedrine also permits independent dose titration.4,11,12... 

Topical and systemic decongestants are sympathomimetic agents that act on adrenergic receptors in the nasal mucosa to produce vasoconstriction, shrink swollen mucosa, and improve ventilation. Decongestants work well in combination with antihistamines when nasal congestion is part of the clinical picture. 

Some oral products combine antihistamines with sympathomimetic decongestants and are marketed for nasal congestion associated with hayfever and the common cold. 

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