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Naratriptan

C 4H 5BrN2 116480-53-6) see Naratriptan 2-bromo-4 -methylvalerophenone (CjjHisBrO) see Pyrovalerone... [Pg.2315]

C iH FjNO, J254S3-3I-0) see Dolasetron mesilate indole-3-carboxylic acid imidazolide (CiiHoNjO 99445-26-S) see Tropisetron (S)-indoline-2-carboxylic acid (QjH.jNOj 79815-20-6) see Perindopril ( )-2-(lH-indol-5-yl)-A -methylethenesulfonamide (CiiHijNjOjS 98623-49-5) see Naratriptan 5-(3-indolylmcthyl)hydantoin (Ci2H N,02 21753-16-2) see L-Tryptophan... [Pg.2402]

Direct attenuation of the excitability of neurons in the trigeminal nuclei, as 5-HTib/ 5-HTid receptors on pain transmission neurons in the trigeminal nucleus caudalis and in the upper cervical cord, are activated. Stimulation of these receptors is caused by second-generation triptans that cross the blood-brain barrier such as zolmitriptan, naratriptan, rizatriptan and eletriptan. [Pg.458]

Naratriptan Oral tablets 1, 2.5 2.5 4 hours Substrate CYP450... [Pg.507]

Hoskin, K. L., Lambert, G. A., Donaldson, C. and Zagami, A. S. The 5-hydroxytryptamine1B/iD/iF receptor agonists eletriptan and naratriptan inhibit trigeminovascular input to the nucleus tractus solitarius in the cat. Brain Res. 998 91-99, 2004. [Pg.248]

Naratriptan 1 or 2.5 mg at onset can repeat after 4 hours if needed Optimal dose is 2.5 mg maximum daily dose is 5 mg... [Pg.617]

Sumatriptan, zolmitriptan, naratriptan, rizatriptan, almotriptan, fro-vatriptan, and eletriptan are appropriate first-line therapies for patients with moderate to severe migraine or as rescue therapy when nonspecific medications are ineffective. [Pg.619]

Antimigraines Sumatriptan, naratriptan, zolmitriptan, rizatriptan Vishwanathan et al. (2000)... [Pg.167]

Vishwanathan K, Bartlett MG, Stewart JT. 2000. Determination of antimigraine compounds rizatriptan, zolmitriptan, naratriptan and sumatriptan in human serum by liquid chromatography/electrospray tandem mass spectrometry. Rapid Commun Mass Spectrom 14 168. [Pg.176]

Renai/hepatic function impairment- The use of naratriptan is contraindicated... [Pg.959]

Pharmacology Naratriptan, rizatriptan, sumatriptan, frovatriptan, almotriptan, eletriptan, and zolmitriptan are selective agonists for a vascular 5-hydroxytryptamine-i(serotonin) receptor subtype. Use of 5-HT- agonists results in... [Pg.962]

Naratriptan and sumatriptan Cerebrovascular or peripheral vascular syndromes, severe hepatic impairment (Child-Pugh grade C) severe renal impairment (Ccr less than 15 mL/min) (naratriptan only). [Pg.964]

Lactation Sumatriptan and eletriptan are excreted in breast milk. Zolmitriptan, naratriptan, almotriptan, frovatriptan, and rizatriptan are excreted in rat milk. Children Safety and efficacy in children have not been established. 5-HT- receptor... [Pg.966]

Corneal opacities Sumatriptan, eletriptan, naratriptan, and almotriptan cause corneal opacities and defects in dogs, raising the possibility that these changes may occur in humans. [Pg.966]

Eletriptan (Relpax) Frovatriptan (Frova) Naratriptan (Amerge) Sumatriptan (Imitrex) Zolmitriptan (Zomig)... [Pg.54]

Uses Obesity Action Blocks uptake of norepinephrine, serotonin, dopamine Dose 10 mg/d PO, may to 5 mg after 4 wk Caution [C, -] w/ SSRIs, Li, dextromethorphan, opioids Contra MAOI w/in 14 d, uncontrolled HTN, arrhythmias Disp Caps SE HA, insomnia, xerostomia, constipation, rhinitis, tach, HTN Interactions T Risk of serotonin synd W/ dextromethorphan, ergots, fentanyl, Li, meperidine, MAOIs, naratriptan, pentazocine, rizatriptan, sumatriptan, SSRIs, tryptophan, zolmitriptan, St. John s wort effects W/ cimetidine, erythromycin, ketoconazole T CNS depression W/ EtOH EMS Use fentanyl w/ caution, may T risk of serotonin synd concurrent EtOH use can T CNS depression OD May cause tach, HTN, diaphoresis, HA, fever, agitation, muscle tremors, and Szs symptomatic and supportive... [Pg.282]

See other pages where Naratriptan is mentioned: [Pg.1124]    [Pg.1124]    [Pg.1403]    [Pg.1403]    [Pg.1404]    [Pg.1404]    [Pg.1404]    [Pg.2314]    [Pg.2314]    [Pg.2393]    [Pg.2398]    [Pg.2418]    [Pg.2418]    [Pg.2421]    [Pg.2421]    [Pg.2424]    [Pg.593]    [Pg.611]    [Pg.620]    [Pg.594]    [Pg.613]    [Pg.263]    [Pg.41]    [Pg.81]    [Pg.447]    [Pg.9]    [Pg.68]    [Pg.957]    [Pg.959]    [Pg.963]    [Pg.232]    [Pg.232]   
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Dihydroergotamine Naratriptan

Hormonal) Naratriptan

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Naratriptan SSRIs)

Naratriptan hydrochloride

Naratriptan pharmacokinetics

Naratriptan synthesis

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