Nanoparticle protein-encapsuled

The cores of individual mammalian ferritin molecules are clearly visible by transmission electron microscopy as well defined nanoparticle crystallites encapsulated within the protein shell which can attain a size close to that of the 8 nm interior diameter of the protein shell (Massover, 1993). This is illustrated in Figure 6.13 for a sample of human ferritin. The amount of iron in the core is variable, and can range from zero to a maximum of approximately 4500 atoms (Fischbach and Anderegg, 1965) this corresponds to the capacity of the internal cavity for Fe(III) as... 

Kida T, Inoue K, Akagi T et al (2007) Preparation of novel polysaccharide nanoparticles by the self-assembly of amphiphilic pectins and their protein-encapsulation ability. Chem Lett 36 940-941... 

Akagi T, Shima F, Akashi M (2011) Intracellular degradation and distribution of protein-encapsulated amphiphilic poly(amino acid) nanoparticles. Biomaterials 32 4959 1967... 

The ability of chitosan nanoparticles to encapsulate these molecules was seen to be very high. To obtain the desired final protein loading, it was sufficient to adjust... 

Gu J, Huang K, Zhu X, Li Y, Wei J, Zhao W, Liu C, Shi J (2013) Sub-150nm mesoporous silica nanoparticles with tunable pore sizes and well-ordered mesostructure for protein encapsulation. J Colloid Interface Sci 407 236-242... 

Protein encapsulated alginate microspheres [214] or collagen nanoparticles [215] Bovine serum albumin (BSA) and nerve growth factor (NGF) -a sustained release of BSA was achieved over an 11-day period, and NGF over a thirty-day period in-vitro Composite hydrogel The full biocompatibility, the adequate mechanical strength and excellent optical clarity gave them possible use as therapeutic lenses for drug delivery and as corneal substitute for transplantation into patients who have corneal diseases. 

N. Rescignano, L. Tarpani, R. Tiribuzi, S. Montesano, S. Martino, L. Latterini, J.M. Kenny, and 1. Armentano, Protein encapsulation in biodegradable polymeric nanoparticles Morphology, fluorescence behaviour and stem cell uptake, Macromolecular Bioscience, 13, 1204-12, 2013. 

T. Feczkd, et al.. Optimization of protein encapsulation in PLGA nanoparticles. Chemical Engineering and Processing Process Intensification, 50 (8) 757-765,2011. 

Portilla-Arias JA, Camargo B, Garcia-Alvarez M et al (2009) Nanoparticles made of microbial poly(y-glutamate)s for encapsulation and delivery of drugs and proteins. J Biomater Sci Polym Ed 20 1065-1079... 

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