N-tert-Butyl nitrone

The same conclusions about the effect of substituents and protonation on chemical a-C shift have been made from the spectra of a-substituted N-tert-butyl-nitrones (388). 

Durand G, Polidori A, Puccio B. Nouveaux Derives Amphiphiles de L Alpha-C-Phenyl-N-tert-Butyl Nitrone, French Patent No. 2846968, May 14, 2004. 

Milatovic, D., Zivin, M., Dettbam, W-D. (2000b). The spin trapping agent phenyl-N-tert-butyl-nitrone (PBN) prevents excitotoxicity in skeletal muscle. Neurosci. Lett. 278 25-8. 

Miyajima, T., Kotake, Y. (1997). Spin trap phenyl N-tert-butyl-nitrone (PBN) for the inhibition of nitric oxide synthase induction in mice. Free Radio. Biol. Med. 22 463-70. 

Jaeger and Bard using a spin trapping technique (with a-phenyl N-tert-butyl nitrone, PBN, and a-(4-pyridyl N-oxide) N-tert-butyl nitrone, 4-POBN, as spin traps), have detected hydroxyl, OH, and perhydroxyl, HO2, radicals during band-gap irradiation of aqueous suspensions of Ti02 and platinised Ti02 powders. Titanium dioxide employed was a pre-reduced anatase powder and the experiments were performed in... 

In regard to the reactions of cation radicals with stable radicals, such as l,l-diphenyl-2-picrylhydrazyl, and with well-known spin traps, virtually nothing can be found in the literature. The pyridine cation radical has been reported to add to the spin trap phenyl-N-tert-butyl nitrone (37). 

Trapping free radicals by the spin trapping technique. This technique is used for the detection and identification of short-lived free radicals by detecting the ESR spectra of nitroxyl addition products (spin adducts) of free radicals (R ) to nitroso (e.g. 2-nitroso-2-methyl propane, t-butyl nitroxide 10.19), nitrobenzene (10.20), pentamethylnitrobenzene (10.21)) and nitrone (phenyl-N-tert-butyl nitrone) (10.22) compounds called spin traps ... 

N-tert-Butyl a-phenyl nitrone [3376-24-7] M 177.2, m 73-74 . Crystd from hexane. 

TeNT. See Tetanus neurotoxin N-Tert-butyl-(2-sulfophenyal)-nitrone (S-PBN), 417 Tetanus neurotoxin, 266 THC. See Delta-9-tetrahydrocannabinol Thiazolidinediones, 171 3a,5a-THP... 

Benzoesaure 4-Brom- -diethyl-amid E5, 979 (Nf - CO-NR2) Nitron C-(4-Brom-phenyl)-N-tert.-butyl- E14b, 1409 (aus R2NH)... 

Nitron N-tert.-Butyl-C-(4-nitro-phe-nyl)- E14b, 1409/1414 (aus R2NH), 1421 (aus lmin) Piperidin-l-oxid l-[2(bzw. 4)-Nitro-phenyl]- El6a, 419 (Amin-Oxidat.)... 

Nitron N-tert.-Butyl-C-(4-trifluor-methyl-phenyl)- E14b, 1414 (aus R2NH)... 

Hydroxylamin N-tert.-Butyl-N-[2-(3-chlor-4-nitro-phenyl)-ethyl]-E16a, 163 (Nitron-Red.)... 

Nitron ( )-N-tert.-Butyl-C-ethoxy-C-phenyl- El4b, 1406 (aus R-CO-NR-OH) 7-Oxa-6-nza-tricyclo[6.3.1.0 dode-can (12S)-( )-(1a,8 )-12-Allyl-... 

C11H1202 1-(4-methylphenyl)-1 -cyclopropanecarboxylic B3846-66-e 23.57 1.0695 2 22076 CIIHI4N263 N-tert-butyl-alpha-(4-nitrophenyl)nitrone 3585-88-4 25.00 1.1934 2... 

N-tert-Butyl a-phenyl nitrone (PBN) [3376-24-7] M 177.2, m 73-74 . Crystallise PBN from hexane. It is a free radical trap. [cflsazsaMethods Enzymology 105 188 1984, Beilstein 7IV 519.]... 

No current spin trap comes anywhere near these ideals thus the choice of an appropriate spin trap for the studies being carried out is of crucial importance. Fortunately recent advances have provided some major steps towards this ideal situation. In order to simplify the discussion and comparison between the new traps and older established agents, these traps have been grouped into families based on three commonly used traps - those related to the cyclic nitrone 5,5-dimethyl-1-pyrroline N-oxide (1, DMPO), those related to the acyclic nitrone N-tert-butyl-a-phenylnitrone (49, PBN), and nitroso traps. In each case data are provided, in a table format, on the currently perceived advantages and disadvantages of these new traps relative to existing compounds. 

Recently, tert- butyl (phenylsulfonyl)alkyl-A-hydroxycarbamates (343), which are readily obtained from the reaction of aldehydes and tert -butyl-A -hydroxy-carbamate in an aqueous methanol solution, were used as an equivalent of N -(/iocprotected nitrones in the nucleophilic addition of Grignard reagents (Scheme 2.144) (571). 

Piperidin 4-tert.-Butyl-1-hydroxy-E16a, 164 (Nitron-Red ), 197 (N-Oxid-Red. C,N-Spaltung) Propan 3-Amino-l-cyclohexyloxy-IV/lc, 125 f. 

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