N-acety

OH NHAc N-acety/neuraminic acid r ( COOH OH NHAC 1... 

Fig. 2.44 The N-0 turn formed from N-acety-lated a-aminooxy carboxamides of D-config-uration 169. Schematic representation of the N-0 turn with representative NOEs found in ROESY of 169c in CDCI3 and the X-ray crystal structure of 169c. The intramolecular H-bond is characterized by a short H- O distance of...

Maps and Conformational Transitions Between Low-Energy Conformers of N-Acety 1-N -Methyl Glycine Amide An Ab Initio Study at the 4-21G Lever with Gradient Relaxed Geometries. J. Mol. Struct. (Theochem) 124, 143-153. 

A. nigen Cultures were dosed and then 20 mg ml-1 Residual N- N-acety lphenoth iazine [51]... 

Probably, one of the most valuable advances in this field has dealt with the first chemoenzymatic synthesis of the stable isotope-enriched heparin from a uniformly double labelled 13C, 15N /V-acetylheparosan from E. coli K5. Heteronuclear, multidimensional nuclear magnetic resonance spectroscopy was employed to analyze the chemical composition and solution conformation of N-acety 1 hcparosan, the precursors, and heparin. Isotopic enrichment was found to provide well-resolved 13C spectra with the high sensitivity required for conformational studies of these biomolecules. Stable isotope-labelled heparin was indistinguishable from heparin derived from animal tissues and might be employed as a novel tool for studying the interaction of heparin with different receptors.30... 

Carboxy-benzimidazole decarboxylieren bereitwillig allein beim Erwarmen unter N-Acety-lierung in Acetanhydrid427. 

Deterding, L. J., Srinivas, P., Mahmood, N. A., Burka, L. T., and Tomer, K. B. (1989). Fast atom bombardment and tandem mass spectrometry for structure determination of cysteine, N- acety I cyste i n e, and glutathione adducts of xenobiotics. Anal. Biochem. 183 94-107. 

Baslow M. H. (2000). Functions of N-acety 1-L-aspartate and N-acetyl-L-aspartylglutamate in the vertebrate brain role in glial cell-specific signaling. J. Neurochem. 75 453 459. 

Moree, W. J., Schouten, A., Kroon, J., and Liskamp, R. M. J. (1995) Peptides containing the sulfonamide transition-state isostere synthesis and structure of N-acety 1 -tarvI -L-proline methylamide. Ini. J. Pept. Prot. Res. 45, 501-507. 

Another example came from the Wong group [24], To synthesize the S SEA-4 hexasaccharide 94, they started from the dibutyl sialyl phosphate 91, which was coupled to thioglycoside 92 with TMSOTf as the activator (Scheme 6.18). The N-acety-lated oxazolidinone moiety in donor 91 was crucial for the high a selectivity in the sialylation reaction. Subsequent coupling to acceptor 93 in the presence of NIS afforded 94 in 78% yield for the two steps. 

Fig. 5.—(a) Overall, 500-MHz, H-N.m.r. Spectrum of Compound 5. (b) Expanded, Structural-reporter-group Regions of the Resolution-enhanced, 500-MHz, H-N.m.r. Spectrum of Compound 5. [The bold numbers in the spectra refer to the corresponding residues in the structure. Signals of corresponding protons in the a and /3 anomer of 5, occurring in this anomeric mixture in the ratio of 2 1, coincide, unless otherwise indicated. The relative-intensity scale of the expanded, N-acety 1-proton region differs from that of the other parts of the spectrum, as indicated.]... 

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