Cell-specific signaling

Baslow MH (2000) Functions of W-acetyl-L-aspartatc and W-acetyl-L-asparty[glutamate in the vertebrate brain role in glial cell-specific signaling. J Neurochem 75 453—459... 

Liu YF, Albert PR. Cell-specific signaling of the 5-HT1A receptor. Modulation by protein kinases C and A. J Biol Chem 1991 266 23,689-23,697. 

Presumably via coupling to different G-proteins, dopamine D2 receptors in various cell lines revealed that they utilise different signal transduction systems (for reviews see refs. 21, 25). Inhibition of adenylyl cyclase has been detected in all cellular environments,30 45 51 but cell-specific signalling pathways may be present as well. Beside inhibition of intracellular cAMP production, stimulation of dopamine D2 receptors may result in (1) enhancement of phosphatidylinositol (PI) hydrolysis by activation of the enzyme phospholipase C 49 51 (2) increase48 49 51 or decrease51 in the intracellular Ca2+ concentration (3) opening of K+ channels 51 and (4) extracellular release of arachidonic acid.48 52... 

Various optimizations were carried out to improve the cell-specific signal. Aptamer-probe concentrations ranging from 1 nM to 0.1 pM were attempted in the presence of a minute concentration of splint (400pM Fig. 2). The same probe dilution series was also performed in the presence of even smaller splint concentrations of 40pM and 4pM (Fig. 3). Overall, it is difficult to... 

Pollen allelopathy is phenomenon when pollen chemicals (e.g., phenols, terpenoids, sesquiterpene lactones, etc.) inhibit sexual reproduction in heterospecific individuals due to influencing of fertilization (Murphy 1992). The phenomenon includes excretion of signaling compounds from the donor cell (pollens, pistil stigma), recognition of a specific signal, transmission of information (pollen), and the development of a characteristic response in the acceptor cell. The possible mechanism of the effect was described in Roshchina (2001). 

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