Myrtenic acid

Rabbits metabolized myrtenal (6 ) to myrtenic acid (7 ) as the major metabolite and myrtanol (8a or 8b ) as the minor metabolite (Ishida et al., 1981b) (Figure 19.168). 

C with agitation and aeration for 4 days yielded camphor (37 ), bomeol (36a ), isobomeol (36b ), a-terpineol (34 ), and P-isopropyl pimelic acid (248 ) (see Figure 14.154). Using modified Czapek-Dox medium and keeping the other conditions the same, the pattern of the metabolic products was dramatically changed. The metabolites were tran -pinocarveol (2 ), myrtenol (S ), a-fenchol (11 ), a-terpineol (34 ), myrtenic acid (7 ), and two unidentified products (see Figure 14.157). 

Occurs in eucalyptus and other plant oils. Unstable oil with cinnamon odour. Bpjj 99-100°. [a] -1-14.75°. 10-Carboxylic acid [601-74-1]. 2-Pinen-lO-oic acid. Myrtenic acid C10H14O2 M 166.219... 

Fig. 3.22 BonabiUnes, unique alkaloids from the roots of Bonamia spectabilis (Convolvulaceae) highlighted in grey, structurally related components of certain (non-convolvulaceous) essential oils for comparison. a-Pinene, myrtenol, and myrtenal are constituents of the essential oil of Myrtus communis L., Myrtaceae (Savikin-Fodulovic et al. 2000) the corresponding carboxylic acid, myrtenic acid, was detected as a constituent of the essential oil of Cedronella canariensis (L.) Webb. Berthel., Lamiaceae (Engel et al. 1995)...

Several oxygenated derivatives based on pinane have been found to occur in woody parts. For example, myrtenol (100), myrtenal (101) and myrtenic acid (102) have been isolated from wood of Chamaecyparis formosensis. (-)-trans-Pinocarveol (103) is present in American gum turpentine. (+)-c/5 -Verbenol (104), its trans isomer, and (+)-tra/w-verbenone (105) are important components of frankincense from Boswellia cartevii (275 vol. Ill b, c, 296, 379). From the roots of Paeonia albiflora, a few highly oxygenated pinane derivatives (e.g., paeoniflo-rin, 106) have been obtained (223). 

The essential oil contains mainly pinocam-phone, isopinocamphone, a- and P-pinenes, camphene, and a-terpinene, which together constitute about 70% of the oil. Other constituents present include pinocampheol, cineole, linalool, terpineol, terpinyl acetate, bomyl acetate, cw-pinic acid, cw-pinonic acid, myrtenic acid, myrtenol methyl ether, (i-2-hyckoxy-isopinocamphone, methyl myr-tenate, cadinene, and other unidentified compounds totaling more than 50 (karrer list... 

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