Myriastra clavosa

Fu, X. Schmitz, F.J. Kelly-Borges, M. McCready, T.L. Holmes, C.F.B. (1998A) Clavosines A-C from the marine sponge Myriastra clavosa. Potent cytotoxins and inhibitors of protein phosphatases 1 and 2A. J. Nat. Prod., 63, 7957-63. 

The prevalent Microcystis aeruginosa has afforded the plasmin inhibitors micropeptins 478-A (1115) and 478-B (1116) (1133). The terrestrial cyanobacterium Scytonema hofmanni PCC 7110 gives rise to scyptolins A (1117) and B (1118), which contain the 3-chloro-A-methyltyrosine residue (1134). The binding of 1117 to pancreatic elastase has been determined by X-ray crystallography (1135). Myriastramide B (1119) was isolated from the Philippine sponge Myriastra clavosa and features a novel chlorinated ether moiety (1136). 

Rao, M.R. and Eaulkner, D.J. (2002a) Clavosolides A and B, dimeric macrolides from the Philippines sponge Myriastra clavosa. J. Nat. Prod., 65, 366-368. 

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