Myo-inositol, oxidation

Karkonen, A., 2005. Biosynthesis of UDP-AlcA Via UDPGDH or the/myo/-inositol oxidation pathway Plant Biosystems, 139 46-49. 

Loewus, F., Chen, M.-S., and Loewus, M.W., 1973, The myo-inositol oxidation pathway to cell wall polysaccharides. In Loewus, F. (ed.), Biogenesis of Plant Cell Wall Polysaccharides. Academic press, New York, pp. 1-27. 

Loewus, M.W., and Loewus, F.A., 1980, The C-5 hydrogen isotope effect in myo-inositol 1-phosphate synthase as evidence for the myo-inositol oxidation pathway. Carbohydr. Res. 83 333-342. 

Rosenfield, C.-L., and Loewus, F.A., 1978a, Metabolic studies on intermediates in the myo-inositol oxidation pathway in Lilium longiflorum pollen. II. Evidence for the participation of uridine diphosphoxylose and free xylose as intermediates. Plant Physiol. 61 96-100. 

Base-catalyzed nitromethane cyclizadonof the thaldehyde generated by periodate oxidation of 1,3-O-cyclohexyhdene-myo-inositol affords the nitrodiol with l,4/3,3,5-coti iguration This is converted into the ct-marmosidase inhibitor, marmostadn A fEq 3 60 ... 

Figure 1. Proton magnetic resonance spectra at 14.1, 23.5, and 51.7 kilo gauss (60, 100 and 220 MHz.) of myo-inositol in deuterium oxide.

Carless HAJ, Oak OZ (1991) Total synthesis of (-)-laminitol (lD-4C-methyl-myo-inositol) via microbial oxidation of tolnene. Tetrahedron Lett 32 1671-1674. 

Base-catalyzed nitromethane cyclization of the dialdehyde generated by periodate oxidation of 1,2-O-cyclohexylidene-myo-inositol affords the nitrodiol with 1,4/2,3,5-configuration. This is converted into the a-mannosidase inhibitor, mannostatin A (Eq. 3.60).98... 

M. Santoro, E. Caffaratti, J. M. Salas-Peregrin, L. Korecz, A. Rockenbauer, L. Sala, and S. Signorella, Kinetics and mechanism of the chromic oxidation of myo-inositol, Polyhedron, 26 (2007) 169-177. 

Complete structural analysis of galactinol by the methylation method was reported66 by Kabat and associates in 1953. On hydrolysis, completely methylated galactinol gives 2,3,4,6-tetra-O-methyl-D-galactose (identified as the anilide) and 2,3,4,5,6-penta-O-methyl-D-myo-inositol (identified by oxidation to the penta-O-methylinosose, reduction, and demethylation, to give mpo-inositol and L-inositol). 

Pseudomonas putida oxidation of benzene affords cis-3,5-cyclohexadiene-l,2-diol which is used as a novel precursor for the synthesis of D- and L-myo-inositol trisphosphates, which was prepared in 11 steps ... 

Arner, R.J., Prabhu, S., Thompson, J.T., Hildenbrandt, G.R., Liken, A.D., and Reddy, C.C., 2001, myo-Inositol oxygenase Molecular cloning and expression of a unique enzyme that oxidizes myo-inositol and D-c/uro-inositol. Biochem. J. 360 313-320. 

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