Mustard long-term health effects

After completion of Volume 1, three new panels were established to Identify and assess evidence on the possible long-term health effects or delayed sequelae of the three chemical classes tested. This was done over a period of a year, during which each panel met three times. Pertinent material was examined to evaluate the possibility that experimental exposure of soldiers may have resulted in untoward health effects. The three panels were separately concerned with four cholinesterase reactivator chemicals (oximes) two types of psychochemicals (phencyclidine and dlmethylheptylpyran and congeners), administered In pure form, as opposed to street drugs and mustard gas and several lacrlmatory and respiratory irritants (such as CN, CS, CR, and CA). 

PS is acutely toxic and has a variety of sensory effects in animals. It has not been evaluated thoroughly for mutagenicity or carcinogenicity. Like those exposed to mustard gas, the subjects exposed to PS were wearing gas masks, and small numbers of soldiers were exposed to small doses. PS is unlikely to have produced detectable long-term health effects in volunteers exposed at Edgewood. 

Sidell, F.R., Hurst, C.G. (1997). Long-term health effects of nerve agents and mustard. In Textbook of Military Medicine -Medical Aspects of Chemical and Biological Warfare (R. Zajtchuk, R.F. Bellamy, eds), pp. 229 6. Office of the Surgeon General, Deptirtment of the Army, Washington, DC. 

Smith, K.J., Hurst, C.G., Moeller, R.B., Skelton, H.G., Sidell, F.R. (1995). Sulfur mustard its continuing threat as a chemical warfare agent, the cutaneous lesions induced, progress in understanding its mechanism of action, its long-term health effects, and new developments for protection and therapy. J. Am. Acad. Dermatol. 32 16S-16. 

LONG-TERM HEALTH EFFECTS OF NERVE AGENTS AND MUSTARD... 

Long-Term Health Effects of Nerve Agents and Mustard... 

Available information implicates the nerve agents and mustard as the cause or probable cause of several long-term health effects. 

Effects of Mustard Gas Exposure in Pediatric Patients Long-Term Health Status of Mustard-Exposed Children, 14 Years After Chemical Bombardment of Sardasht... 

CDC (Centers for Disease Control and Prevention). 1988. Final Recommendations for Protecting Health and Safety Against Potential Adverse Effects of Long-Term Exposure to Low Doses of Agents GA, GB, VX Mustard Agent (H, HD, T) and Lewisite (L). Federal Register, Vol. 53, No. 50, March 15. 

DHHS (US Department of Health and Human Services) (1988). Final recommendations for protecting the health and safety against potential adverse effects of long-term exposure to low doses of agents GA, GB, VX, mustard agent (H, HD, HT), and lewisite (L). US Department of Health and Human Services, Centers for Disease Control. Fed. Reg. 53(50) 8504-7. 

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