Murine acquired immunodeficiency

Murine leukemia virus LP-BM5 MuLV is known to induce a remarkable immunodeficiency syndrome in C57BL/6 mice [18]. The syndrome caused by this virus is called murine acquired immunodeficiency syndrome (MAIDS). This virus also causes an early selective defect in CD4+ Th-cell function, and some whose symptoms are similar to those found in AIDS patients [19]. MAIDS mice are a useful model for elucidating the mechanism of depressed resistance to opportunistic pathogens common in AIDS patients [20-21],... 

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