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Multistage tumorigenesis

Cell transformation can occur at very high frequencies in vitro. [Pg.557]

Joyce JA, Baruch A, Chehade K et al (2004) Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumorigenesis. Cancer Cell 5 443-453... [Pg.42]

Figure 24.27. Mouse skin model of multistage carcinogenesis. Genetic changes associated with mouse skin tumorigenesis. Figure 24.27. Mouse skin model of multistage carcinogenesis. Genetic changes associated with mouse skin tumorigenesis.
Initiation-Promotion Studies. Carcinogenesis has been demonstrated to be a multistage process in the cells of certain animal tissues, including skin. lung, liver, and bladder. This process is believed to occur in human tumorigenesis as well. The PAHs have been studied extensively for their ability to act as tumor initiators and/or promoters. Following is a brief discussion, by chemical, ofthe results of the initiation-promotion studies performed with 13 of the 17 PAHs discussed in this profile. Only those studies considered adequate and reliable are presented in Table 2- 3. [Pg.79]

See other pages where Multistage tumorigenesis is mentioned: [Pg.557]    [Pg.557]    [Pg.557]    [Pg.559]    [Pg.561]    [Pg.418]    [Pg.557]    [Pg.557]    [Pg.557]    [Pg.559]    [Pg.561]    [Pg.418]    [Pg.332]    [Pg.11]    [Pg.185]    [Pg.153]    [Pg.55]    [Pg.78]    [Pg.396]    [Pg.477]    [Pg.230]    [Pg.130]   
See also in sourсe #XX -- [ Pg.557 , Pg.558 ]



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