Multiple Sclerosis Functional Composite

Rates functional systems from 0 (normal) to 10 (death due to MS) Emphasis is on ambulation over other symptoms Multiple Sclerosis Functional Composite (MSFQ Three-part tool rating ambulation, limb function, and cognitive function... 

ALT, alanine aminotransferase AST, aspartate aminotransferase EDSS, Expanded Disability Status Scale MSFC, Multiple Sclerosis Functional Composite. 

The Multiple Sclerosis Functional Composite (MSFC) was developed by the MS Consortium (Whitaker et al., 1995) for evaluating disabilities ranging from motor function to cognitive changes and to replace the EDSS. The three tools included in the MSFC are a timed 25 foot walk, the 9-hole peg test for hand dexterity and the Paced Auditory Serial Addition Test (PASAT). The MSFC is a quandfiable measure of disability but ten years later, it is sdll infrequently incorporated as a primary outcome measure because of the increased time element necessary to validate the individual tests and the dme necessary for their adminisd adon. 

The Multiple Sclerosis Functional Composite (MSFC) does not test... 

PASAT paced auditory sequential addition test is a segment of the multiple sclerosis functional composite that tests one component of cognitive function. 

Rudick RA, Cutter G, Reingold S. The multiple sclerosis functional composite A new clinical outcome measure for multiple sclerosis trials. Mult Scler 2002 8 359-365. 

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