Multiple-core approach applications

Other Applications of the Multiple-Core Approach. The bulk of this chapter has dealt with the specific application of multiple-core methodology to questions of atmospheric Hg deposition. Whole-basin Hg accumulation rates for seven lakes, calculated from multiple sediment cores, were used in a simple mass-balance model to estimate atmospheric fluxes and Hg transport from catchment soils. This approach can be used to answer other limnological questions, and the model is not restricted to Hg or atmospheric deposition. 

For the core LIMS, one must be careful not to be lulled into a false sense of security by the supplier s claim that the software is a standard product. What this usually means is that a set of software modules has been used in at least one or perhaps a few other LIMS installations. In this case, we must pose the question, "Is it really standard or in fact bespoke " The approach that should be taken to these "standard modules" is to determine if they are indeed standard (i.e., they are not revised to fit your LIMS application and have multiple applications for which references are available). If they are not standard, then confirm that the supplier has performed a Source Code Review or a suitable design review. If no review has been performed, the pharmaceutical manufacturer will need to make a value judgment on the risk this imposes (taking into account the results of the GLP assessment) and, if necessary, request that the supplier perform a Source Code Review as part of the project. 

This section has nsed select examples from the Uterature to demonstrate the synthesis of precisely controlled dendritic stmetures throngh the spontaneous assembly of multiple components aronnd a multivalent core. This approach has universal application and there are now examples of dendrons that are indneed to assemble around a range of... 

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