Multimodal assemblies

The 6 Nd YAG lasers pump the DM0, preamplifier and power amplifier (Fig. 19, Friedman et al., 1998). The YAG lasers are built from commercially available flashlamp/laser rod assemblies, acousto-optic Q-switches and frequency doubling crystals (LBO and KTP). Most of the mirror mounts and crystal holders are commercial. Nd YAGs are frequency doubled to 532 nm using a nonlinear crystal. The Nd YAG rod and nonlinear crystal are both in the pump laser cavity to provide efficient frequency conversion. The 532 nm light is coupled out through a dichroic and fed to multimode fibers which transport the light to the DM0 and amplifier dye cells. 

Foldamer duplex receptors that assemble through multimodal interactions have been developed in order to generate supramolecular host assemblies for... 

Nanoparticles were also assembled to enable multimodal imaging by loading different imaging contrast agents. For example, MRI-fluorescence imaging was... 

A great deal of effort has been directed toward the development of mnltimodal imaging probes for these reasons. Supramolecnlar chemistry has a pivotal role here in that molecular recognition and self-assembly processes can tremendously impact the sensitivity and specificity of the probes in each individual imaging modality. Here, several examples highlighting supramolecnlar designs of multimodal agents are presented. 

Figure 7.3a is a photograph of the assembled microchip device. Two pairs of multimode optic fibers were integrated with the plastic chip to facilitate multiple wavelength detection of two different types of fluorescence dyes. 

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