Multi-chamber centrifuge

The main types of industrial centrifuges used for bioparticle separations are the tubular, the multi-chamber, and the disc centrifuges Figure 11.8). The disc centrifuge may have nozzles to allow continuous exit of the concentrated suspension. The nozzles allow operation in a continuous mode, with Rf > 0. Tubular and multi-chamber centrifuges operate with... 

The efficiency of the multi-chamber centrifuges is high because of the long residence time of the liquor in the unit. A mathematical model similar to that used for the tubular centrifuge can be applied to the multi-chamber centrifuge provided that satisfactory assumptions and modifications are made. 

The cleaning of multi-chamber centrifuges is more difficult and takes longer than for the tubular type. The manual discharge generally limits this type of machine to suspensions containing less than 4—5% solids by volume. 

Available speeds range between 4500 and 8500 rev. min , flow rates from 2.5 to lOm h and bowl diameters from 335 to 615 mm. Multi-chamber centrifuges, apart from the separation of grinding swarf from cutting oils already mentioned, are mainly used for the clarification of beer, wine, fruit juice and varnishes. 

Figure 4.14. Separation of cell lysates containing pharmaceutical products, employing large-capacity centrifuges that are configured with tubular bowl (A), multi-chamber bowl (B), disc stack bowl (C), or decanter (scroll) bowl (D).

Schematic drawing of centrifuges (A) tubular, (B) multi-chamber, (C) disc centrifuge.

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