MRI cell

Ris, F., Lepetit-Coiffe, M., Meda, P., Crowe, L.A., Toso, C., Armanet, M., et al. Assessment of human islet labeling with clinical grade iron nanoparticles prior to transplantation for graft monitoring by MRI. Cell Transplantation 19, 1573-1585 (2010)... 

R385 J. M. Janjic and E. T. Ahrens, Fluorine-Containing Nanoemulsions for MRI Cell Tracking , Wiley Interdisciplinary Reviews Nanomedicine and Nanotechnology, [online computer file], 2009, 1, 492, Avail. URL http // www3.interscience.wiley.eom/cgi-bin/fulltext/122403160/PDFSTART. 

Guillet-Nicolas, R. et al (2013) Manganese-impregnated mesoporous silica nanoparticles for signal enhancement in MRI cell labelling studies. Nanoscale, 5 (23), 11499-11511. 

The existence of very small energy differences ( 0.5 mRy) between the fct and bcc phase in CuZn, forces us to take a suffir intly large k-mesh with 2500 k-points per cell, whereas for the FeaNi system we may use a much smaller k-mesh (between 500 and 900) for good convergence. In order to get this high precision for the CuZn total... 

Reliable markers are needed to monitor the activity of antiangiogenic dtugs. Circulating endothelial cells and their progenitor subset are a potential candidate, as is MRI dynamic measurement of vascular permeability/ flow in response to angiogenesis inhibitors, but neither has been clinically validated. 

The neurointerventionalist should limit the number of microcatheter injections performed during the exam, as there is growing evidence that this may increase the chances of hemorrhagic transformation of the infarcted tissue. Direct injection of contrast into stagnant vessels, which contains injured glial cells and thus breakdown of the blood-brain barrier, allows for contrast extravasation. Contrast is readily visualized on the immediate post-thrombolysis CT as an area of high attenuation in the parenchyma. In some instances, MRI with susceptibility-weighted sequences may be useful to differentiate contrast extravasation from Such a distinction... 

In a different way, metallic-core nanoparticles [346-349] (prepared cf. Section 3.10) equipped with biocompatible coats such as L-cysteine or dextrane may be exploited for highly efficient and cell-specific cancer cell targeting, i.e., for improving diagnosis and therapy of human cancer. In a recent proof-of-principle experiment an unexpectedly low toxicity of the L-cysteine-covered cobalt nanoparticles was demonstrated [433] For diagnostic purposes, it is expected to use the advantageous magnetic properties of the metallic-core nanoparticles to obtain a contrast medium for MRI with considerably increased sensitivity, capable to detect micro-metastases in the environment of healthy tissues [434 37]. 

Fig. 4.4.9 (a) A new paradigm for MRI veloci- efficient post-processing of MRI data, (b) metry based on prior knowledge. The introduc- Efficient reconstruction of Taylor-Couette cells tion of mathematical constraints imposed by on the longitudinal plane (r, z) starting from... 

Annexin V-functionalized crosslinked iron oxide (CLIO) was designed as a contrast agent for MRI, which was additionally labeled with Cy5.5 to allow colocalization with optical imaging techniques [98]. Alternatively, conjugation of multiple Gd-DTPA molecules or SPIO particles to the C2 domain of synaptotagmin I was shown to allow the detection of apoptotic cells in vitro [99]. Zhao et al. [100] were the first to apply a C2 domain-functionalized SPIO and showed very promising results for future in vivo applications of MR contrast agents for the detection of apoptotic sites. 

Pressure drop and dispersion were the focus of work by Magnico (2003) who simulated flow at lower Re by direct numerical simulation (DNS) in beds of spheres with an in-house code. Tobis (2000) simulated a small cluster of four spheres with inserts between them to compare to his experimental measurements of pressure drop. Gunjal et al. (2005) also focused on flow and pressure drop through a small cell of spheres, in order to validate the CFD approach by comparison to the MRI measurements in the same geometry made by Suekane... 

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