Walking motors

Molloy, J.E. Veigel, C. (2003) Myosin motors walk the walk. Science 300, 2045-2046. 

Solutions of MTs can be driven by kinesin motors to form astral patterns that are reminiscent of the poles of the mitotic spindle. This process is a special case of pattern formation in nonequilibrium systems. It is not hard to see that such patterns can form when motors walk to the end of one filament and then drag this end toward the corresponding end of the other filament they are connected to. Various models have been developed for nonequilibrium, or active gels of this kind.i= -i= ... 

The eleetrieal system eonsisted of a walk-in motor eontrol eenter that eontained the generator breaker and all the neeessary generator... 

A MDP-IA HVAC A Rx cooler 3A No heat removal Pump motor burnout in 3-10 corttinuous service hours Shift walk around No wamine for faults AC and SWS suppirt AVsIemv of I1VA( monitored but not HX... 

Dynein, kinesin, and myosin are motor proteins with ATPase activity that convert the chemical bond energy released by ATP hydrolysis into mechanical work. Each motor molecule reacts cyclically with a polymerized cytoskeletal filament in this chemomechanical transduction process. The motor protein first binds to the filament and then undergoes a conformational change that produces an increment of movement, known as the power stroke. The motor protein then releases its hold on the filament before reattaching at a new site to begin another cycle. Events in the mechanical cycle are believed to depend on intermediate steps in the ATPase cycle. Cytoplasmic dynein and kinesin walk (albeit in opposite... 

Alexi collected his football from his room and then met up with three of his friends, Robin, Clayton and Furat. They walked up the path at the rear of the local sports club which led to the woods. As they entered the woods Alexi saw something amongst the bushes about ten yards from the path. He and his friends found that it was a mini motor bike. The keys were in the ignition and the engine was warm. They pulled the bike free and wondered what to do next. (A)... 

The infants gross motor milestones were obtained well within the normal range. However, observations of their early attempts to walk independently revealed awkward leg movements and placement of their feet. These movements improved over time as did the total arm movements. 

Metachromatic leukodystrophy is due to a defect in arylsulfatase A (ASA). There are three major forms late infantile, juvenile and adult. The overall incidence is 1 40,000. In the late infantile and early juvenile forms, which comprise about 80% of patients, the initial symptoms involve the motor system, with falls, loss of ability to walk, flaccid paralysis, difficulty in swallowing, loss of speech, vision, seizures, decerebrate state and death 1-7 years after onset of symptoms. In the adolescent and... 

Tremors of the hands and sleep disturbances in the form of vivid dreams, nightmares, and insomnia have been reported in association with the use of amiodarone. Ataxia, staggering, and impaired walking have been noted. Peripheral sensory and motor neuropathy or severe proximal muscle weakness develops infrequently. Both neuropathic and myopathic changes are observed on biopsy. Neurological symptoms resolve or improve within several weeks of dosage reduction. 

Fig. 12.8. The Inchworm . It consists of an alumina shaft, slid inside a piezoelectric tube, which consists of three sections. Top, a photograph of the Microlnchworm Motor, actual size. Right, walking mechanism (1) Clamp the left-hand side by applying a voltage to section 1. (2) Extend section 2. (3)...

Interactions such as surface tension also become more influential at smaller scales. Surface tension is due to attractions between molecules, such as electrical charges and hydrogen bonds, which cause them to bunch together and resist separation. For example, such forces create a tension on the surface of water because the molecules stick together, and this force is strong enough to let a bug known as the water strider walk on water. In Zetd s motor, the smaller drop grows imtil it reaches... 

Two other considerations of taking a shorter route are the time that can be saved and the rates at which each leg of the journey are traveled. Some people can walk faster than they can row a boat, but others can really move through the water. Also, if the boat has a motor, then water travel may be the more efficient, but a bicycle or car can change the whole scenario. 

Did you ever see a dream walking asks the popular 1940s love song, Well, I did. And so did Carlos Schenck and Mark Mahowald when they recorded patients with the REM sleep behavior disorder (RBD) in their sleep lab. In chapter 8, I described the dramatic emergence in the REM sleep of some middle-aged people of motor acts that bore a 1 1 relationship to the subjective experience of dream movement. 

Uses. Intrathecal baclofen can result in decreased spasticity and increased comfort in many people with severe spasticity. This intervention can also result in functional improvements, especially in cases where voluntary motor control was being masked by spasticity.16 Ambulatory patients with spasticity resulting from a CVA, for example, may be able to increase their walking speed and increase their functional mobility after intrathecal baclofen therapy.37,74... 

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