Mothers milk bromide transfer through

Vobecky M, Babicky A and Pavelka S (2003) Bromide transfer through mother s milk and its impact on the suckling rat. Pood Chem Toxicol, submitted. 

Iodine Transfer Through Mother s Milk The Influence of Bromide... 

Figure 20.2 shows the results of a similar experiment, in which the transfer of Br-bromide through mothers milk into the body of the suckling was followed (Vobecky et al., 2005). As anticipated, radioactive bromide appeared in the body of the young in the course of the first 3 h after its application to the mother. 

Although bromide passed easily through mother s milk into the body of the young, this transfer occurred at a much slower rate than the transfer of iodide (cf, Figures 20.1 and 20.2). In the case of iodide, nearly 30% of radioactivity applied to the mother (in the form of radioiodide) appeared in the body of the young in the course... 

Figure 20.2 Time course of the transfer of 2Br-bromide from dams to the young through mother s milk. Six lactating rats, each kept with a nest of eight young and maintained on a standard diet and tap water, were given approximately 2.3 MBq 82Br in the form of potassium bromide (0.17 mg Br) in 0.3 ml saline by subcutaneous injection on day 12 after delivery. The whole-body radioactivity of the dams and that of the whole nests was measured in vivo at 3, 6, 12 and 25h after radiobromide application by means of a gamma-spectrometric system equipped with an HPGe detector. Modified with permission from Vobecky et ai, (2005).

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