Moore, Stanford

Moore, Stanford, 1030 Morphine, biosynthesis of, 969 specific rotation of, 296 structure of, 64 MR1, see Magnetic resonance imaging. 468-469 mRNA, see Messenger RNA MS, see Mass spectrometry Mullis, Kary Banks, 1117 Multiplct (NMR), 460 table of, 462... 

Moore, Stanford. (1913-1982). An American biochemist who won the Nobel Prize for chemistry in 1972, with Anfinsen and Stein, for enzyme studies. He was involved with the analysis of the action of the complex enzyme deoxyribonuclease. His Ph.D. was granted from the University of Wisconsin. 

Moore, Stanford (1913-1982), American biochemist and winner of the Nobel Prize for Chemistry in 1972 (shared with An-finsen and Stein) for his contribution to the understanding of the connection between chemical structure and catalytic activity of the active center of the ribonuclease molecule. He received his Ph.D in organic... 

William Howard Stein fl 911-1980) was born in New York City and received his Ph.D. in 1938 from the Columbia College of Physicians and Surgeons. He immediately joined the faculty of the Rockefeller Institute, where he remained until his death. In 1972, he shared the Nobel Prize in chemistry for his work with Stanford Moore on developing methods of amino acid analysis and for determining the structure of ribonuclease. 

Stanford Moore (1913-1982) was born in Chicago, Illinois, and received his Ph.D. from the University of Wisconsin in 1938. He was a professor at the Rockefeller Institute and shared the 1972 Nobel Prize in chemistry with his colleague and collaborator, William Stein. 

The experimental work was carried out at Stanford Research Institute in 1966-67 under USAF Contract No. AF33(615)-3248. The author acknowledges the contributions of R. A. Dickie, F. J. Martinelli, and R. L. Moore. 

Stanford Moore United States chemical structure and catalytic activity... 

M.A. Cook etal, TrFaradSoc 56, 1028-38(1960 Promotion of shock initiation of detonation by metallic surfaces) 36a) Andreev Belyaev (i960), 265-68 (Starting impulse and mechanism of initiation) 268-70 (Initiation by heat) 270-73 (Initiation by flame) 273-86 (Initiation by shock or friction) 287-89 (Initiation of expln in projectiles on hitting a target) 36b) J. Favier C. Fauquignon, MP 42, 65-81(1960) (Initiation of expls. and transmission of detonation) 37) D.B. Moore J.C. Rice, Detonation of Secondary Explosives by Lead Azide , SRI (Stanford Research Institute), Poulter Laboratories, Technical Report 004-60(1960) 37a) S.J. Jacobs, AmRocket-... 

In the words of Poulter Moore of Stanford Research Institute (quoted in Ref 4, p 197) "A normal shock pulse traveling in an inert medium is continuously doing work on the medium thru which it is traveling, and hence is continuously being attenuated and therefore decelerated. A detonation is a true shock pulse, but one in which the energy lost in attenuation. is being replaced by the energy released by the chemical reaction associated with the detonation pro-... 

The fourth student in this group, Stanford Moore, began his doctoral thesis research with Link in 1935. His work involved the development of a new, and still useful, procedure for oxidizing aldoses to the aldonic acids by potassium hypoiodite in methanol solution the resulting aldonic acids were then converted into nicely crystalline benzimidazole derivatives that proved more suitable for the characterization of carbohydrates than the classical osazones. This method, developed by Moore and Link (1940), was extended to the characterization of hexuronic acids, as their bis(benzimidazole)s, after oxidation to the glycaric acid (R. Lohmar, Dimler, Moore, and Link, 1942), of lactic acid (Moore, Dimler, and Link, 1941 Dimler and Link, 1942), and of ribose, fucose, and digitoxose (Dimler and Link, 1943). During these... 

ANFINSEN, CHRISTIAN B. (1916-1995). An American biochemist who won the Nobel prize for chemistry- in 1972 for his work on ribonuclease, especially concerning the connection between the amino acid sequence and die biologically active conformation. He shared the Nobel prize with Stanford Moore and William H. Stein. His doctorate was granted from Harvard. 

Ribonucleases are a widely distributed family of en-zymes that hydrolyze RNA by cutting the P—O ester bond attached to a ribose 5 carbon (fig. 8.12). A good representative of the family is the pancreatic enzyme ribonuclease A (RNase A), which is specific for a pyrimidine base (uracil or cytosine) on the 3 side of the phosphate bond that is cleaved. When the amino acid sequence of bovine RNase A was determined in 1960 by Stanford Moore and William Stein, it was the first enzyme and only the second protein to be sequenced. RNase A thus played an important role in the development of ideas about enzymatic catalysis. It was one of the first enzymes to have its three-dimensional structure elucidated by x-ray diffraction and was also the first to be synthesized completely from its amino acids. The synthetic protein proved to be enzymatically indistinguishable from the native enzyme. 

Stanford Moore Rockefeller Univ., amino acid sequence of lysozyme... 

Moore, 1977a] Moore, F. R. (1977a). Real Time Interactive Computer Music Synthesis. PhD thesis, Stanford University, EE Dept. 

Anderson, B., Moore, A., and Cohn, D. A. "Presented at International Conference on Machine Learning 2000", Stanford University, CA, USA (2000). 

I want to first acknowledge my debt to those distinguished educators who have valiantly tried to provide me with insight into chemistry and biochemistry. They include Professor Charles D. Anderson of Pacific Lutheran University, Tacoma, Washington, Professor Earl W. Davie of the University of Washington, Seattle, and Professors Stanford Moore and William Stein of the Rockefeller Institute, New York. 

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