Moods limbic system

Nerve signals from the thalamus and the reticular formation are transmitted to the limbic system as well as the hypothalamus. Together, these regions of the brain are responsible for behavioral and emotional responses to pain. The limbic system, in particular, may be involved with the mood-altering and attention-narrowing effect of pain. 

The role of these agents, either as primary or adjunctive treatments for mood disorders, has yet to be fully explored ( 106, 108, 279, 280 and 281). Theories have included the differential effects of clozapine on dopamine receptor subtypes (e.g., increased activity at the receptors, which exist in high density in the limbic system) and the greater 5-HT2 to D2 antagonism of most novel agents in comparison with neuroleptics (282). More recently, controlled trials indicate that novel antispychotics (NAPs) may play an important and perhaps unique role for more severe, psychotic, and/or refractory mood disorders ( 112, 283, 384). 

Emotional distress—including anxiety, depressed mood, and irritability—is a pervasive feature of cannabis withdrawal in human subjects (Budney et al., 2003, 2004 Vandrey et al., 2005, 2008). Likewise, pharmacologically induced cannabi-noid withdrawal in rats is associated with marked anxiety-related behavioral and physiological responses, as well as with activation of CRF-mediated transmission in the limbic system (Rodriguez de Fonseca et al., 1997). 

People are essentially visually oriented, and dependent on sight and sound to gather information from the surroundings. Smell, however, is an extraordinary sense. Closely linked to the limbic system (seat of emotions and the functions of memory), it has the power above all other senses to transport us, in an instant, to times past or pervade our psyche to change our mood. Only now is science starting to understand how this sense works, and scientists are discovering that it may be the most complex sense of all. 

Profile of mood states limbic system for emotional memory... 

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