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Monopril

Fosipress (Menarini) Tensogard (Bristol It. Sud) Monopril (Bristol-Myers Squibb)... [Pg.939]

There are instances where the reflux temperature decreases with conversion of the reagents, and exothermic reactions may even lead to hazardous runaway conditions. In such cases it may become necessary to optimize an addition sequence of reagents to avoid unwanted exotherms. Anderson et al. (1997) have given a practical example for an important intermediate in making the drug monopril. [Pg.183]

Monopressure processes, in nitric acid production, 17 175, 176 Monopril, molecular formula and structure, 5 150t... [Pg.602]

Fosfomycin (Monurol) Antibiotic Fosinopril (Monopril) ACE-inhibitor... [Pg.27]

Floxifral, Faverin, Luvox Foldine, Folvite, Leucovorin Foscavir Monopril... [Pg.340]

USAN Fosinopril sodium Trade name Monopril ... [Pg.144]

Oral 2.5, 5, 10, 20 mg tablets Parenteral (Enalaprilat) 1.25 mg/mL for injection Fosinopril (generic, Monopril)... [Pg.247]

Benazepril (Lotensin) Captopril (Capoten) Enalapril (Vasotec) Fosinopril (Monopril) Lisinopril (Prinivil, Zestril) Moexipril (Univasc) Perindopril (Aceon) Quinapril (Accupril) Ramipril (Altace) Trandolapril (Mavik)... [Pg.296]

Angiotensin-converting enzyme (ACE) inhibitors, such as benazepril (Lotensin), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), quinapril (Accupril), and ramipril (Altace). [Pg.48]

Later drugs included enalapril (Vasotec, 2.10) and fosinopril (Monopril, 2.11). ACE inhibitors quickly displaced /3-blockers as the leading antihypertensive drugs in the 1980s.4... [Pg.17]

The 5 -(-)-2-cyclohexy 1-1,3-propanediol monoacetate (24) and the S-( )-2-phenyl-1,3-propanediol monoacetate (25) are key chiral intermediates for the chemoenzymatic synthesis of Monopril (26) (Fig. 10), a new antihypertensive drug which acts as an ACE inhibitor. The asymmetric hydrolysis of 2-cyclohexyl-1,3-propanediol diacetate (27) and 2-phenyl-1,3-propanediol diacetate (28) to the corresponding S-( - )-monoacetate (24) and S-( )-monoacetate (25) by porcine pancreatic lipase (PPL) and Chromobacterium viscosum lipase have been demon-... [Pg.152]

Figure 10 Preparation of chiral synthon for monopril asymmetric enzymatic hydrolysis of 2-cyclohexyl- and 2-phenyl-1,3-propanediol diacetate (27) and (28) to the corresponding S-(—)-monoacetates. Figure 10 Preparation of chiral synthon for monopril asymmetric enzymatic hydrolysis of 2-cyclohexyl- and 2-phenyl-1,3-propanediol diacetate (27) and (28) to the corresponding S-(—)-monoacetates.
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Fosinopril sodium Monopril

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