Monoethyl fumarate

Monoethyl fumarate Fumarlc acid, monoethyl ester (8) 2-Butened1o1c acid (E)-, nxinoethyl ester (9) (2459-05-4)... 

A 500-mL, one-necked flask, equipped with a calcium chloride drying tube is charged with 28.83 g (0.20 mol) of monoethyl fumarate (Note 1), 200 mL of... 

Monoethyl fumarate was purchased from Ega-Chemie, D-7924 Stelnheim, Germany. 

The copolymer of glycidyl methacrylate and methyl methacrylate was treated with a mixture of monoethyl fumarate and cinnamic acid to yield a polymer capable of [2 + 2] cycloaddition with the naphthylacrylate as well as cinnamate-cinnamate and cinnamate-fumarate crosslinks. 

Topical monoethyl fumarate caused contact dermatitis in a patient with atopic eczema and a generalized, partly pustulous, exanthema in a patient with psoriasis (10). The authors suggested that the mechanism was non-immunological contact urticaria. 

In 12 healthy volunteers, topical monoethyl fumarate caused spontaneous persistent erythema and systemic administration caused flushing (11). In patients with... 

Fig. 12a,b H spectra of a L-alanine and b monoethyl fumarate obtained with the pulse sequence RI82, with cji/27r = 135 kHz and cjr/27r = 20kHz. The H Larmor frequency was 400 MHz (Reproduced with permission from Ref. [53])... 

To measure high-resolution spectra of disordered samples, the anisotropy of the chemical shift must be eliminated in addition to the homonuclear dipole-dipole interaction. This can be achieved for abundant nuclei by combined rotation and multi-pulse spectroscopy (CRAMPS), which is the combination of homonuclear multi-pulse spectroscopy and MAS [Bur2, Ger2, Sch6]. In Fig. 3.3.13, H spectra of monoethyl fumarate are compared for different NMR techniques [Brol]. Only the combination of MAS and multi-pulse excitation produces a high-resolution spectrum of the polycrystalline powder. 

Full details for the preparation of ethyl 4-hydroxycrotonate [ (243) R=H] from monoethyl fumarate have been given. The... 

A 500-mL, one-necked flask, equipped with a calcium chloride drying tube is charged with 28,83 g (0.20 mol) of monoethyl fumarate (Note 1), 200 mL of dry dichloromethane (Note 2), 44.47 g (0.60 mol) of tert-butyl alcohol (Note 3) and 2.00 g (0.16 mol) of 4-dimethy 1 aminopyridine (Note 4). The solution Is stirred and cooled in an ice bath to 0°C while 45.59 g (0.22 mol) of dicyclohexylcarbodiimide (Note 5) is added over a 5-min period. After a further 5 min at 0°C the ice bath is removed and the dark brown reaction mixture is stirred for 3 hr at room temperature. Dicyclohexyl urea which has precipitated is removed by filtration through a fritted Buchner funnel (S3), and the filtrate is washed with two 50-mL portions of 0,5 N hydrochloric acid... 

CAS 2459-05-4 EINECS/ELINCS 219-544-7 Synonyms Monoethyl fumarate Empincai CeH804 Formula CzHgOCOCHiCHCOOH Properties M.w. 144.13 m.p. 67-69 C Uses Fungistat in tomato juice Manuf./Distrib. Aldrich http //www.sigma-aidrich.com Fluka http //www.sigma-aidrich.com... 

Monoethanolethylenediamine. See Aminoethylethanolamine Monoethylamine. See Ethylamine Monoethyl aniline. See N-Ethylaniline Monoethylene glycol. See Ethylene glycol Monoethylene glycol dimethyl ether. See Ethylene glycol dimethyl ether Monoethyl fumarate. See Ethyl fumarate Mono (2-ethylhexyl) adipate CAS 4337-65-9... 

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