Monocyte transmigration

Navab, M., Imes, S.S., Hama, S.Y., Hough, G.P., Ross, L.A., Bork, R.W., Valente, A.J., Berliner, J.A., Drinkwater, D.C., Laks, H. and Fogelman, A.M. (1991). Monocyte transmigration induced by modification of low density lipoprotein in cocultures of human aortic endothelial cells is due to induction of monocyte chemotactic protein 1 synthesis and is abolished by high density lipoprotein. J. Clin. Invest. 88, 2039-2046. 

Martin-Padura I, Lostaglio S, Schneemann M, Williams L, Romano M, Fruscella P, Panzeri C, Stoppacciaro A, Ruco L, Villa A, Simmons D, and Dejana E [1998] Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration. J Cell Biol 142 117-127... 

Ishikawa, K. et al. Induction of heme oxygenase-1 inhibits the monocyte transmigration induced by mildly oxidized LDL. J. Clin. Invest. 100 (1997) 1209-16. 

Weiss JM, Nath A, Major EO, Berman JW. HIV-l Tat induces monocyte chemoattractant protein-1-mediated monocyte transmigration across a model of the human blood-brain barrier and up-regulates CCR5 expression on human monocytes. J Immunol 1999 163 2953-2959. 

Hashimoto, K., Kataoka, N., Nakamura, E., Hagihara, K., Okamoto, T., Kanouchi, H., et al. (2012). Live-cell visualization of the trans-ceUular mode of monocyte transmigration across the vascular endothelium, and its relationship with endothehal PECAM-1. The Journal of Physiological Sciences, 62(1), 63-69. 

Weber KS, von Hundelshausen P, Clark-Lewis 1, Weber PC, Weber C (1999) Differential immobilization and hierarchical involvement of chemokines in monocyte arrest and transmigration on inflamed endothelium in shear flow. Eur J Immunol 29(2) 700-712 Wesselingh SL, Power C, Glass JD, Tyor WR, McArthur JC, Farber JM, Griffin JW, Griffin DE (1993) Intracerebral cytokine messenger RNA expression in acquired immunodeficiency syndrome dementia. Ann Neurol 33(6) 576-582... 

A more selective inhibition of NFkB can be achieved by transfecting cells with DNA coding for the natural inhibitor IkBo or a mutant IkB protein that lacks 36 N-terminal amino acids, and consequently becomes proteolysis resistant. In this way expression of adhesion molecules and monocyte adhesion and transmigration can be inhibited [87,88], The potentials and limitations of these latter types of therapy are however not fully understood as yet. Different transfection systems (adenoviral, retroviral, non-viral) are available for gene delivery purposes, all with their own potentials and restrictions. 

Klouche M, May A E, Hemmes M, et al. (1999) Enzymatically modified, nonoxidized LDL induces selective adhesion and transmigration of monocytes and T-lymphocytes through human endothelial cell monolayers. Arterioscler ThrombArterioscler Thromb Vase Biol 19 784-793... 

Muller, W.A. and Randolph, G.J. (1999). Migration of leukocytes across the endothelium and beyond molecules involved in the transmigration and fate of monocytes. J. Leuk. Biol. 66, 698-704. 

Muller, W. A., Weigh S. A. (1992). Monocyte-selective transendothehal migration Dissection of the binding and transmigration phases by an in vitro assay. TheJournal of Experimental Medicine, 176(3), 819—828. 

FIGURE 15.4 Oxysterols may upregulate all steps in the transmigration of lenkocytes through the endothelial layer lining the arterial vessels. VCAM-1, vascular cell adhesion molecule-1 ICAM-1, intercellular adhesion molecule-1 MCP-1, monocyte chemotactic protein-1 MIP, monocyte inflammatory protein. 

Weiss, J. M., Downie, S. A., Lyman, W. D., and Berman, J. W. (1998). Astrocyte-derived monocyte-chemoattractant protein-1 directs the transmigration of leukocytes across a model of the human blood-brain barrier. J. Immunol 161, 6896-6903. 

Weerasinghe D, McHugh KP, Ross FP, Brown EJ, Gisler RH, Imhof BA. A role for the alphavbeta3 integrin in the transmigration of monocytes. J Cell Biol 1998 142 595-607. 

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