Multiple target molecules

Chene P (2008) Challenges in design of biochemical assays for the identification of small molecules to target multiple conformations of protein kinases. Drug Discov Today 13 522-529... 

In keeping with the basic tenet of supramolecular chemistry, that it is chemistry beyond the molecule , any therapy that claims to work through a supramolecular mechanism must involve multiple target specific interactions. Furthermore the nature of the interactions should be non-covalent. 

Fig. 3 Typical microarray-based assay. A microarray is incubated with a solution containing multiple target molecules. After removal of unbound molecules, the target-bound microarray is stained with fluorescence, followed by imaging and quantification...

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