Molecular genetic approach, fungal

In addition to optimizing fermentation parameters, fungal strain improvement and selection, either by classical mutagenesis or more sophisticated targeted molecular genetic approaches, are important research avenues to increase productivity and yield of industrial fermentations (Ruijter et al, 2002). 

Tsukahara, K. et al. 2003. Medicinal genetics approach towards identifying the molecular target of a novel inhibitor of fungal cell wall assembly. Mol. Microbiol. 48,1029-1042. 

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