Molecular building blocks groups

Life as we know it depends on this existence of water as a liquid. Biochemical processes require free movement of chemicals, which cannot occur in the solid phase. Biochemical stmctures contain many interlocking parts that would not be stable in the gas phase. Thus, the liquid phase is best suited for life. Moreover, water is an excellent solvent, particularly for molecules that can form hydrogen bonds. As we describe in Chapter JA, the molecular building blocks of living matter are rich in groups that form hydrogen bonds. This allows biological molecules to be synthesized, move about, and assemble into complex structures, all in aqueous solution. 

These seven groups of compounds, and the diversity of compounds within each group, are the molecular building blocks that enable structure and function. A brief overview of the relevant biochemistry for each class is pertinent to an appreciation of their role in medicinal chemistry and drug design. 

The distinctive properties of the nanostructures are determined by the respective functional groups attached to the molecular building block ... 

Therefore, in the supramolecular design, molecular building blocks should be devised, incorporating suitable functional groups for their effective coupling. In... 

One of the attractions of supramolecular chemistry is the extraordinary potential for synthesis of new materials that can be achieved much more rapidly and more effectively than with conventional covalent means. For supramolecular synthesis to advance, it is obviously important to characterize, classify, and analyze structural patterns, space group frequencies, and symmetry operators [118], However, at the same time we also need to bring together this information with the explicit aim of improving and developing supramolecular synthesis - the deliberate combination of different discrete molecular building blocks within periodic crystalline materials. 

---