Molecular Biology of the Cell

In contrast, RNA occurs in multiple copies and various forms (Table 11.2). Cells contain up to eight times as much RNA as DNA. RNA has a number of important biological functions, and on this basis, RNA molecules are categorized into several major types messenger RNA, ribosomal RNA, and transfer RNA. Eukaryotic cells contain an additional type, small nuclear RNA (snRNA). With these basic definitions in mind, let s now briefly consider the chemical and structural nature of DNA and the various RNAs. Chapter 12 elaborates on methods to determine the primary structure of nucleic acids by sequencing methods and discusses the secondary and tertiary structures of DNA and RNA. Part rV, Information Transfer, includes a detailed treatment of the dynamic role of nucleic acids in the molecular biology of the cell. 

Alberts B, Bray D, Lewis J et al (1994) Molecular biology of the cell. Garland, New York... 

B Alberts, D Bray, J Lewis, M Raff, K Roberts, ID Watson. Molecular Biology of the Cell. 3rd ed. New York Garlaud, 1994. 

Figure 41-10. Schematic representation of types of transport systems. Transporters can be classified with regard to the direction of movement and whether one or more unique molecules are moved. (Redrawn and reproduced, with permission, from Alberts B et al Molecular Biology of the Cell. Garland, 1983.)...

Alberts B, Johnson A, Lewis J, Raff M, Walter P. 2002. Molecular Biology of the Cell. 4th ed. New York Garland Science. 

B. Alberts, D. Bray, J. Lewis, M. Raff, K. Roberts, and J. D. Watson, Molecular Biology of the Cell, 3rd edn., Garland Publishing, New York, 1994. 

Ruth Ganli Division of Molecular Biology of the Cell German Cancer Research Center Heidelberg, Germany... 

Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., and Walters, P. (2002) The Shape and Structure of Proteins, Molecular Biology of the Cell, 4th edn. Garland Science, New York and London. 

Rajagopal, A. and Simon, S.M. (2003) Suhcellular localization and activity of multidrug resistance proteins. Molecular Biology of the Cell, 14, 3389—3399. 

Figure 16.1 a schematic representation illustrating the chemical reactions that interconvert small molecules in cells. Each dot represents a compound and the lines that connect them represent reactions. The heavy dots and lines down the center of the maze reflect the glycolytic pathway and the heavy circle near the bottom of the maze reflects the citric acid cycle. ( 2007 From Molecular Biology of the Cell, 5th Edition, by Alberts et al. Reproduced by permission of Garland Science/Taylor Francis, EEC.)... 

Michishita, E., Park, J.Y., Bumeskis, J.M., Barrett, J.C. and Horikawa, I. (2005) Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins. Molecular Biology of the Cell, 16, 4623 35. 

Alberts, B., A. Johnson Julian Lewis, Martin Raff, et al. Molecular Biology of the Cell 4 ed. New York, NY Garland Publishing, 2002. 

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