Modulating factors anthocyanins

Several animal and human studies have already associated biological effects with anthocyanin consumption, but for that to happen, the compounds or their metabolites must reach target tissues. BioavaUability is sometimes taken as guaranteed, and the mechanisms by which molecules are avaUable, the factors that modulate this bioavailabihty and the chemical forms that may have bioactivity are not adequately explored. These questions still remain with few, unclear, and broad informations as an answer. 

More studies should be carried out in what concerns anthocyanin transport across biological membranes. There are studies aimouncing neuroprotective effects of anthocyanin-rich foods, but there is a gap in the knowledge concerning, for example, anthocyanin (and metabolites) transport across blood-brain barrier. On top of this, it is urgent to know dietary factors able to modulate anthocyanin bioavailability, helping health professionals to make dietary recommendations. These recommendations will be relevant for a healthy life but also to alert medical doctors as to possible pharmacological interactions with anthocyanins. 

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