Mobile Wad

Owing to a differential diagnosis list which mainly includes wrist problems (i.e., de Quervain disease and Wartenberg neuropathy), the most important tendinopathy of the mobile wad compartment affecting the tendons of the extensor carpi radialis brevis and longus as they traverse the components of the first dorsal extensor tendon compartment, so-called intersection syndrome, will be discussed in Chapter 10. 

Wad and Kramer [35] described an HPLC method for simultaneous determination of vigabatrin and gabapentin in serum and urine after precolumn derivatization with o-phthaldialdehyde and fluorimetric detection at 455 nm with excitation at 230 nm. A column (12.5 cm x 3.0 mm) of Superspher 60 RP-Selected B (5 /im) with acetonitrile in 20 mM 0.5 M KH7PO4 as a mobile phase (flow rate 0.7 ml/min). The day-to-day CV of vigabatrin in a pooled serum was 3.1%. The lower limit of detection was 0.5 /(mol/1 and the calibration graph was rectilinear from 1300 /tmol/1. 

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