Mixing, pastes continuous type

The next case to be considered is the ideal continuous stirred tank reactor. The key to the derivation of the F(t) curve for this type of reactor is the realization that the assumption of perfect mixing implies that upon entry in the reactor an element of volume can instantaneously appear in any portion of the reactor. Therefore its past or its future history cannot be derived from its position. Furthermore, the prob-... 

Of the analytical techniques available for process analytical measmements, IR is one of the most versatile, where all physical forms of a sample may be considered - gases, liquids, solids and even mixed phase materials. A wide range of sample interfaces (sampling accessories) have been developed for infrared spectroscopy over the past 20 to 30 years and many of these can be adapted for either near-lme/at-lme production control or on-line process monitoring applications. For continuous on-line measurements applications may be limited to liquids and gases. However, for applications that have human interaction, such as near-line measurements, then all material types can be considered. For continuous measurements sample condition, as it exists within the process, may be an issue and factors such as temperature, pressure, chemical interfer-ants (such as solvents), and particulate matter may need to be addressed. In off-line applications this may be addressed by the way that the sample is handled, but for continuous on-line process applications this has to be accommodated by a sampling system. 

Fig. 5.16. A screw-type extruder used in continuous wet granulation of pharmaceuticals — the Rietz Extructor. (Courtesy Rietz Division, Bepex Corporation.) Zone 1, premixing zone 2, paste formation zone 3, intense mixing and dispersal zone 4, orifice discharge for size and mixing control.

Paste adhesives. Paste adhesive formulations are produced by mixing the base resin with low-molecular weight diluents or solvents, if necessary, to reduce viscosity. Other prepolymer resins may be added and agitated until dissolved. Viscosity and temperature are continuously monitored and more diluents or resin added as required. Finally, one or more types of fillers are added and mixed and the viscosity of the mixture is adjusted. In incorporating the filler into the resin, best results are obtained when the filler is preheated... 

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