Mini-chip analysis

Also shown in Figures 5.19(c) is the further improvement in dynamic range noted throngh Mini-chip analysis. This is an alternative analysis methodology dis-cnssed farther in Section 5.3.2.3.5. 

Mini-chip analysis as depicted schematically in Figure 5.21(c)... 

Mini-chip analysis is an in situ method (Criegem and Weitzel 1986) that describes the analysis of a ehip of similar dimensions as the analysis area, i.e. in the range of 10 pm X 10 pm to 100 pm x 100 pm. This highly specific type of... 

Figure 5.21 Pictorial illustrations of (a) sample rotation, (b) Backside SIMS, (c) Mini-chip SIMS, and (d) Bevel analysis.

Biological microchips (biochips) are revolutionizing gene expression analysis and classical genotyping as well as diagnostics and testing. Tlie worldwide markets for biochips are primarily composed of DNA chips, protein chips and laboratory chips. Generally, anays are differentiated from microfluidic systems, which can actively operate analysis, separation and synthetic processes by means of microscopic capillary systems, mini-pumps and mini-valves. Tliese are often called a Tab-on-a-chip . 

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