Microwave Synthesis and Medicinal Chemistry

The bottleneck of conventional parallel/combinatorial synthesis is typically optimization of reaction conditions to afford the desired products in suitable yields and purities. Since many reaction sequences require at least one or more heating steps for extended time periods, these optimizations are often difficult and time-consum- 

Microwaves in Organic and Medicinal Chemistry. C. Oliver Kappe, Alexander Stadler Copyright 2005 WILEY-VCH Verlag GmbH Co. KGaA, Weinheim ISBN 3-527-31210-2 

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