Microreactors chemical synthesis

A., Overbeck, S., Implications of microreactors on chemical synthesis, in Proceedings of the VDE World Microtechnologies Congress, MICRO.tec 2000, pp. 489 91 (25-27 September 2000), VDE Verlag, Berlin, EXPO Hannover. 

DeWitt SH (1999) Microreactors for Chemical Synthesis. Curr Opin Chem Biol 3 350-356... 

There are many reasons why chemical synthesis is advantageously performed in flow mode using a micro-contactor (or microreactor) rather than in a round-bottomed flask, well or vessel. In fact, if it was not for a long history of batch mode chemistry and the convenience of a handsized flask, the case would need to be made for employing batch methods. 

Integrating chemical analysis methods and physical sensors with microreactors enables monitoring of reaction conditions and composition. This ability renders instrumented microreactors powerful tools for determining chemical kinetics and identifying optimal conditions for chemical reactions. The latter can be achieved by automated feedback-controlled optimization of reaction conditions, which greatly reduces time and materials costs associated with the development of chemical synthesis procedures. 

Microreactors for Chemical Synthesis and Biotechnology - Current Developments and Future Applications... 

---