Microbial metabolism methodology

Blum U (2007) Can data derived from field and laboratory bioassays establish the existence of allelopathic interactions in nature In Fujii Y, Hiradate S (eds) Allelopathy new concepts and methodology. Science Publishers, Enfield, NH, pp 31-38 Blum U, Dalton BR (1985) Effects of ferulic acid, an allelopathic compound, on leaf expansion of cucumber seedlings grown in nutrient culture. J Chem Ecol 11 279-301 Blum U, Dalton BR, Shann JR (1985a) Effects of various mixtures of ferulic acid and some of its microbial metabolic products on cucumber leaf expansion and dry matter in nutrient culture. J Chem Ecol 11 619-641... 

A notorious underestimation of the dynamic properties of microbial and cellular populations results from matching the duration of the respective batch cultivations to the relevant time constant of the biosystem under investigation. However, metabolic regulation of enzyme activities and fluxes often takes place on a time scale of seconds rather than days although the latter may also be true. It is therefore in the scope of promoting biotechnological research to adopt and develop appropriate experimental concepts, methodologies and equipment [397]. 

Microbial methodologies culture enrichment and microbial strain improvement, metabolic engineering, integration of multi-pathways in cells, cell entrapment, functional genomics... 

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