Micro-tweezers

Figure 29, Assembly for micro-ultrafiltration. The tweezers hold the Millipore filter, cut from the strip. The washers are shown be-low the tweezers. In the center, the top and bottom portion of the filter and washer are shown aligned with the Allen screw. An Alien...

A clever way to minimize the unwanted background from the cover plate or the environment is combining laser tweezers and confocal Raman spectroscopy (LTRS) [73, 74], While the single cells are levitated well off the surface and held in the focus of the laser beam the Raman spectral patterns of these cells are recorded with high sensitivity. Another appealing fact is the usage of one laser for both Raman excitation and optical trapping to keep the instrumental efforts as low as possible. Additionally the trapped cells can also be micro-manipulated and moved from one place to another, e.g., from the native matrix to a clean collection chamber. 

The integration of laser tweezers with Raman spectroscopy for optical manipulation and spectroscopic analysis of individual micro- and nanoscopic objects in physics, chemistry, and the life sciences. 

Abstract. Programmable manipulation of particles or cells plays an important role in many biological and medical applications. Here a new programmable micro manipulator, named lab-on-a-display, in which particles are manipulated by optically induced electrokinetic forces generated from an optoelectronic tweezers on a liquid crystal display, is introduced. This optoelectrofluidic platform has been utilized to manipulate various kinds of cells such as blood cells, oocytes, and motile bacteria for several biotechnological applications. 

Chapter 5 Micro Scissors and Tiny Tweezers. ..163 Chapter 16 Reaction Rate and Body ... 

Exploiting feedback control, we can use electroosmotic actuation, which is routine and easy to implement in micro-fluidic devices, to steer cells - a task usually reserved for expensive, delicate, and large laser-tweezer systems. Our results in this area are described in [14—18], and the text below is adapted from these sources. 

Macroscopic objects can be handled by high-precision manipulation tools such as tweezers. However, macroscopic manipulation methods are not suitable for controlling micro- or nanoscale objects with dimensions smaller than... 

Armani M, Chaudhary S, Probst R, Shapiro B (2004) Micro flow control particle tweezers. Proc mTAS, Mahno... 

Ferrari E, Emiliani V, Cojoc D, Garbin V, Zahid M, Durieux C, Coppey-Moisan M, Di Fabrizio E (2005) Biological samples micro-manipulation by means of optical tweezers. Microelectron Eng 78-79 575-581... 

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