Micro-fabrication technology

Burke DT, Burns MA, Mastrangelo C. Micro- fabrication technologies for integrated nucleic acid analysis. Genome Res 1997 7 189-97. 

Micro-fabrication technology and micro-reaction engineering will be explored extensively so that reaction processes can be conducted on much smaller physical scales and with high precision controls. Micro-scale unit operations are likely to gain acceptance for the manufacturing of fine and specialty chemicals. 

Kandlikar SG, Grande W (2002) Evolution of micro-channel flow passages - thermo-hydraudc performance and fabrication technology. In Proceedings of IMECE ASME International Mechanical Engineering Congress and Exposition, New Orleans, 17-22 November 2002, IMECE 2002-32043, pp 1-13... 

ScHLAAK, H. F., Fabrication technologies and economic aspects for components in microtechnology, in Proceedings of the VDE World Microtechnologies Congress, MICRO. tec 2000, pp. 649-653 (25-27 September 2000), VDE Verlag, Berlin, EXPO Hannover. 

In the mid-IR, routine infrared spectroscopy nowadays almost exclusively uses Fourier-transform (FT) spectrometers. This principle is a standard method in modem analytical chemistry45. Although some efforts have been made to design ultra-compact FT-IR spectrometers for use under real-world conditions, standard systems are still too bulky for many applications. A new approach is the use of micro-fabrication techniques. As an example for this technology, a miniature single-pass Fourier transform spectrometer integrated on a 10 x 5 cm optical bench has been demonstrated to be feasible. Based upon a classical Michelson interferometer design, all... 

Building up expertise in this field, EMBL with its data library is well positioned to play an important European role in estabfishing a reference DNA array and SAGE database. In the future, the micro-array technology will be developed also for proteins, applying miniaturization, nanotechnology, micro-fabricated devices and reaction chambers. 

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