Metsulfuron-methyl

Sulfonylurea herbicides ate weak acids and, in general, ate not strongly sorbed to soils. Sorption of chlotsulfuton and metsulfuron—methyl is inversely related to soil pH (407) and is positively correlated to soil organic matter (408). 

The EPA has not issued HAs for any of the sulfonylurea herbicides (269) and data on the occurrence of the sulfonylurea herbicides in SW or GW are not available. Additional sulfonylurea herbicides include bensulfuron [99283-01-9] and metsulfuron, methyl [74223-64-6]. 

Cereals MEKC UV 0.02-0.04 mg kg- 50mM SDS,25mM sodium phosphate (monobasic), pH 6.15 Metsulfuron-methyl, thifensulfuron-methyl, chlorsulfuron, rimsulfuron, tribenuron-methyl 125... 

Restricted access phases are another approach to exploiting the differences in characteristics of analytes. Large analytes are excluded from an internal surface on which an adsorptive stationary phase is present. A herbicide analysis for Metsulfuron methyl, Bentazone, Bromoxynil, methylchlorophenoxy acid, and Mecoprop in the presence of humic acid was performed on restricted access reversed phase media.52 The cytostatic compound epirubicin and its metabolites were separated from plasma using a Pinkerton GFF II column.53 Gradient separations of polymers on reversed phase and on normal phase represent an alternative to gel permeation chromatography. Polyesters of noncrystalline materials were separated on a variety of such phases.54... 

Metropolis Monte Carlo (MMC) method, 26 1035-1036 Met-spar, 4 577 Metsulfuron-methyl, 13 322 Mettler dropping point, 10 827 Mevacor, 5 142... 

Ismail and Lee (1995) studied the persistence of metsulfuron-methyl in a sandy loam (pH 5.1) and clay soil (3.1) under laboratory conditions. Degradation was more rapid in nonsterilized than in sterilized soil. In nonsterilized soil, the rate of degradation increased with increasing soil moisture content. When the moisture level in the sandy loam and clay soil was increased from 20 to 80% of field capacity at 35 °C, the half-lives were reduced from 9.0 to 5.7 and 11.2 to 4.6 d, respectively. The investigators concluded that the disappearance of metsulfuron-methyl in soil resulted from microbial degradation and chemical hydrolysis. 

Berglof, T., Koskinen.W.C., Duffy, M.J., Norberg, K.A., andKylin, H. Metsulfuron methyl sorption-desorption infield-moist soils, J. Agric. Food Chem., 51(12) 3598-3603, 2003. 

Walker, A., Cotterill, E.G., Welch, S.J. (1989) Adsorption and degradation of chlorsulfuron and metsulfuron-methyl in soils from different depths. Weed Res. 29, 281-287. 

Thompson DG, Holmes SB, Wainio-Keizer K, MacDonald L, Solomon KR. 1993a. Impact of hexazinone and metsulfuron methyl on the zooplankton community of a boreal forest lake. Environ Toxicol Chem 12 1709-1717. 

Metribuzin heterocyclic nitrogen, triazine Metsulfovax heterocyclic nitrogen thiazole, amide Metsulfuron-methyl sulfonyl urea Mevinphos phosphoro organic, phosphate ester Mexacarbate carbamate Mirex halogenated hydrocarbon Molinate thiocarbamate Monalide amide... 

Saccharin clorimuron, ethametsulfuron, metsulfuron-methyl, primisulfuron, sulfometuron, tribenuron Saffole piperonyl butoxide... 

C14H15N506S metsulfuron-methyl 74223-64-6 454.15 39.497 1,2 27367 C14H16N40 3-methylpyridine-1-oxide-4-azo-p-dimethyl-an 31932-35-1 553.15 49.014 2... 

General LC/MS Conditions for Sulfonylurea Multiresidue Analysis. We have developed general thermospray LC/MS conditions for the purpose of separating and detecting six different sulfonylurea herbicides. These conditions can be used as a guide fra- a variety of LC/MS residue applications which may require the analysis of one or more of these herbicides. Our procedure includes GLEAN (chlorsulfuron), ALLY (metsulfuron methyl), HARMONY (thiameturon) and EXPRESS cereal herbicides, CLASSIC (chlorimuron ethyl) soybean herbicide and OUST (sulfometuron-methyl) noncrop land herbicide. (Structure 1)... 

Klaffenbach, P. and Holland, P. T. 1993. Analysis of sulfonylurea herbicides by gas-liquid chromatography. 2. Determination of chlorsulfuron and metsulfuron-methyl in soil and water samples, J. Agricul. Food Chem., 41 396-401. 

Lolium biotypes exist which have resistance to the sulfonylurea herbicides chlorsulfuron and metsulfuron methyl (4). The biotype used in the studies presented here is resistant to both these sulfonylurea herbicides. Sulfonylurea herbicides inhibit the chloroplastic enzyme acetolactate synthase (ALS), also known as acetohydroxyacid synthase (AHAS) (16). Inhibition of this enzyme results in disruption of the synthesis of the branched-chain amino acids valine and isoleucine (161. The imidazolinone herbicides also inhibit ALS Q2). In some species auxins can protect against chlorsulfuron inhibition (S. Frear, USDA North Dakota, personal communication) the mechanistic basis for this protection is not known. We have measured the ALS activity in the resistant and susceptible Lolium and have also checked for any induction of ALS activity following treatment with the sulfonylurea herbicide chlorsulfuron. 

The chemical name of DPX-T 6376 is methyl 2-[3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)ureidosuIfonyl]benzoate (metsulfuron-methyl, 2). 

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