Propionaldehyde 2- -2-methyl

Table 2. Reaction of (S)-3-Ben2yloxy-2-fluoro-2-methyl-propionaldehyde with Various Metal Enolates [d]...

C4C14S tetrachlorothiophene 6012-97-1 1.102E-K10 79.800 3535.2 C4H802 3-hydroxy-2-methyl propionaldehyde 38433-80-6 7.870E+09 53.860... 

AI3-15311 CCRIS 1101 EINECS 201-149-6 FEMA No. 2220 HSDB 614 Isobutaldehyde Isobutanal Isobutylaldehyde Isobutyral Isobutyraldehyd Isobutyraldehyde Isobutyric aldehyde Isobutyryl aldehyde, isopropyl aldehyde Isopropyl formaldehyde Isopropylfbrmaldehyde Methylpropanal NCI-C60968 NSC 6739 Propanal, 2-methyl- Propionaldehyde, 2-methyl- UN2045 Valine aidehyde. Used in chemical synthesis. Liquid mp d -65.9° bp n 64.5° d = 0.7891 moderately soluble in H2O, organic soivents LDso (rat orl) = 3700 mg/kg. Eastman Chem. Co. Lancaster Synthesis Co. Mallinckrodt Inc. Sigma-Aldrich Fine Chem. 

Synonyms isobutanal 2-methyl-1-propanal isobutyric aldehyde isobutyl aldehyde 2-methyl propionaldehyde valine aldehyde... 

Some aerobic oxidation reactions progress effectively in SCCO2 without a catalyst. Aerobic oxidation of olefins (e.g. cw-cyclooctene and (/f)-(-F)-limonene) in the presence of aldehydes (e.g. 2-methyl-propionaldehyde) in SCCO2 (d = 0.75 g/mL) gave the corresponding epoxides without a catalyst. It is speculated that the stainless steel from autoclave walls triggered the formation of acylperoxy radicals from the aldehyde and oxygen, and the reaction proceeded via a non-catalytic radical... 

Propionic acid made in butane LPO probably comes by a minor variation of reaction 38 that produces methyl radicals and propionaldehyde. It is estimated that up to 18% of the j -butoxy radicals may decompose in this manner (213) this may be high since propionic acid is a minor product. 

Fiaal purification of propylene oxide is accompHshed by a series of conventional and extractive distillations. Impurities ia the cmde product iaclude water, methyl formate, acetone, methanol, formaldehyde, acetaldehyde, propionaldehyde, and some heavier hydrocarbons. Conventional distillation ia one or two columns separates some of the lower boiling components overhead, while taking some of the higher boilers out the bottom of the column. The reduced level of impurities are then extractively distilled ia one or more columns to provide a purified propylene oxide product. The solvent used for extractive distillation is distilled ia a conventional column to remove the impurities and then recycled (155,156). A variety of extractive solvents have been demonstrated to be effective ia purifyiag propylene oxide, as shown ia Table 4. 

This procedure is representative of a new general method for the preparation of noncyclic acyloins by thiazol ium-catalyzed dimerization of aldehydes in the presence of weak bases (Table I). The advantages of this method over the classical reductive coupling of esters or the modern variation in which the intermediate enediolate is trapped by silylation, are the simplicity of the procedure, the inexpensive materials used, and the purity of the products obtained. For volatile aldehydes such as acetaldehyde and propionaldehyde the reaction Is conducted without solvent in a small, heated autoclave. With the exception of furoin the preparation of benzoins from aromatic aldehydes is best carried out with a different thiazolium catalyst bearing an N-methyl or N-ethyl substituent, instead of the N-benzyl group. Benzoins have usually been prepared by cyanide-catalyzed condensation of aromatic and heterocyclic aldehydes.Unsymnetrical acyloins may be obtained by thiazol1um-catalyzed cross-condensation of two different aldehydes. -1 The thiazolium ion-catalyzed cyclization of 1,5-dialdehydes to cyclic acyloins has been reported. 

Azides can use enamines as dipolarophiles for ],3 cycloadditions to form triazolines. These azides can be formate ester azides (186), phenyl azides (187-195), arylsulfony] azides (191-193,196), or benzoylazides (197,198). For example, the reaction between phenyl azide (138) and the piperidine enamine of propionaldehyde (139) gives 1 -phenyl-4-methy l-5-( 1 -piperidino)-4,5-dihydro-l,2,3-triazole (140), exclusively, in a 53% yield (190). None of the isomeric l-phenyl-5-methyl product was formed. This indicates that the... 

Methyl Trimethylol Methane (Trimethylol-methyl methane, Pentaglycerol or Trimethylol ethane). CH3.C(CH2OH)3, mw 120.17, OB to C02 —173.09%, white cryst, mp 199°, bp 135—37 at 15mm-, sol in uioxane, w Sc ale (Refs 1, 2 4). Prepn from propionaldehyde formalin condensation in cold aq soln using lime 62% yield (Refs 2 3)... 

OL,, -Trinitro-Propionaldehyde methyl imide ( 03,7,7-Trinitro-Propyliden]-methyl-amine). CH3.N CH.CH(N02).CH(N02)2 mw 206.14 N 27.19% white crysts. V sol in acet si sol in w insol in eth. Prepn is by reacting a,j3 J3-trinitro-propionaldehyde suspended in ammonia with an excess of methylammonium chloride. The imide is recovered by acidifying the mixt with HC1... 

The mono K-a, 3,f3-Trinitro-Propionaldehyde-methyl imide salt bright yel cryst explds on heating... 

Propionaldehyde was poured into a container that was intended for collecting residues from different chemical reactions and that already contained methyl methacrylate. The medium detonated not long after this operation and when closing the container. This could be explained (as has already been seen with vinyi acetate) by the fact that propionaidehyde was peroxidised and catalysed the methacrylate polymerisation that could not be controlled. 

ETHYLENE GLYCOL ETHYL MERCAPTAN DIMETHYL SULPHIDE ETHYL AMINE DIMETHYL AMIDE MONOETHANOLAMINE ETHYLENEDIAMINE ACRYLONITRILE PROPADIENE METHYL ACETYLENE ACROLEIN ACRYLIC ACID VINYL FORMATE ALLYL CHLORIDE 1 2 3-TRICHLOROPROPANE PROPIONITRILE CYCLOPROPANE PROPYLENE 1 2-DICHLOROPROPANE ACETONE ALLYL ALCOHOL PROPIONALDEHYDE PROPYLENE OXIDE VINYL METHYL ETHER PROPIONIC ACID ETHYL FORMATE METHYL ACETATE PROPYL CHLORIDE ISOPROPYL CHLORIDE PROPANE... 

Following an incident in which a drum containing bulked drainings (from other drums awaiting reconditioning) finned and later exploded after sealing, it was found that methyl methacrylate and propionaldehyde can, under certain conditions of mixing, lead to a rapid exothermic reaction. Precautions are discussed. 

Figure 5.6 Alcohols, aldehydes, ketones and acids 15, ethylene glycol 16, vinyl alcohol 17, acetaldehyde 18, formaldehyde 19, glyoxal 20, propionaldehyde 21, propionaldehyde 22, acetone 23, ketene 24, formic acid 25, acetic acid 26, methyl formate. (Reproduced from Guillemin et at. 2004 by permission of Elsevier)...

The cobalt-catalyzed hydroformylation of acrolein diacetate in ethanol proceeded in a complicated fashion. The products obtained are listed in Table XXVI. These products are rationalized by the following sequence The initial products formed were m-aldehyde (l,l-diacetoxy-3-formylpro-pane, ca. 60%), isoaldehyde (1,1 -diacetoxy-2-formylpropane, 5-10%) and propionaldehyde diacetate, ca. 5%. In the alcohol solvent, the aldehydes were converted to the corresponding acetals. A portion of the n-aldehyde was converted to 2,5-diethoxytetrahydrofuran by acid catalysis, and the isoaldehyde was thermally decomposed to 2-methyl-3-acetoxyacrolein. 

Nearly quantitative generation of l,3-bis(methylthio)allyllithium was proved, as this solution yielded l,3-bis(methyIthio)propene (88-89%) and l,3-bis(methylthio)-l-butene (89%) by reaction with methanol and methyl iodide, respectively. The checkers found that lithium diisopropylamide can be replaced by w-butyllithium without any trouble for the generation of l,3-bis(methylthio)allyllithium, simplifying the procedure considerably at least in this particular case. Subsequent reaction with propionaldehyde gave l,3-bis(methylthio)-l-hexen-4-ol in 85% yield, and no appreciable amount of by-product, such as the addition product of w-hutyllithium with propionaldehyde or with the intermediate 1.3-bis(methylthio)propene, was formed. 

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