Methyl ethyl ketone precautions

Note Suitable precautions and proper analytical technique should be applied to ensure the accuracy of the weight of the bottle. Before determining its weight, the bottle and its stopper should have been cleaned and dried, then rinsed with methyl ethyl ketone, wiped dry on the outside, dried in the evaporation assembly for about 5 min, and cooled. Then allow it to stand for about 10 min near the balance before weighing. 

Methyl ethyl ketone should be handled in the laboratory using the "basic prudent practices" described in Chapter 5.C, supplemented by the additional precautions for dealing with extremely flammable substances (Chapter 5.F). In particular, MEK should be used only in areas free of ignition sources, and quantities greater than 1 liter should be stored in tightly sealed metal containers in areas separate from oxidizers. 

Many hydrocarbon solvents are flammable and hazardous use special precautions when handling them. Of the reagents used in this procedure, methanol, chloroform, methylene chloride, acetone, methyl ethyl ketone, benzene (see 6.11.1), and n-nonane are hazardous. 

With suitable precautions, to 1 liter of the sodium hydroxylamine disulfonate solution from Preparation 39 2 (approx. 1.2 moles) is added 72 gm (1 mole) of methyl ethyl ketone. The mixture is warmed to TO C. Then the reaction flask is wrapped with insulation and allowed to cool slowly for 12 hr. 

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