Methyl ethyl ketone health effects

Zhao WY, Misumi J, Yasui T, et al. 1998. Effects of methyl ethyl ketone, acetone, or toluene coadministration on 2,5-hexanedione concentration in the sciatic nerve, serum, and urine of rats. Int Arch Occup Environ Health 71 236-244. 

Carlson GP. 1989. Effect of ethanol, carbon tetrachloride, and methyl ethyl ketone on butanol oxidase activity in rat lung and liver. J Toxicol Environ Health 27 255-261. 

Occupational exposure to 2-butoxyetlianol usually involves co-exposure to other solvents and chemicals. In several NIOSH Health Hazard Evaluations, effects reported by workers included eye, nose, and throat irritation coughing runny nose headache dizziness lightheadedness and nausea. Since personal breathing zone and workplace air samples analyzed for solvents and other chemicals (such as toluene, xylene, methyl ethyl ketone, methyl isobutyl ketone, styrene) along with 2-butoxyethanoI indicated that exposure levels for each chemical were below the NIOSH, ACGIH, and OSHA criteria, NIOSH concluded that the effects were probably due to the additive combination of the solvents. 

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