Benzothiazole, 2- -6-methyl

Fig. 7 Structures of the dyes forming aggregates on DNA (a) l-methyI-4-[[3-methyl-2(3//)-benzothiazolylidene]methyl]-quinolinium (Thiazole Orange, TO), (b) 3,3 -diethyIthiadicarbo-cyanine (DiSC2(5)), (c) 3,3 -trimethylammoniopropylthiadicarbocyanine (DiSC3+(5)), (d) 2- [(Z)-2-(2,5-dihydro-2-thienyl)-3 - [3 -methyl-2(3/f)-benzothiazolylidene] -1 -propenyl] -3 -methyl -benzothiazol-3-ium (L-21), (e) 2-[( )-3-[3,7-diethyT6-[( ,2 )-3-(l-ethyl-3,3-dimethyl-3/7-indo-lium-2-yl)-2-propenylidene]-6,7-dihydrothiazolo[5,4-/]benzothiazol-2(3//)-ylidene]-l-propenyl]-l-ethyl-3,3-dimethyl-3//-indolium (BCD), (f) 3-methyl-2-[( )-3-methyl-2-[[3-methyl-2(3/f)-ben-zothiazolylidene]methyl]-l-butenyl]-benzothiazol-3-ium (Cyan ]3iPr)...

Abstract This presentation is a brief review on the resnlts of our work on iodine interaction with thioamides, selenoamides and amides. The thioamides, benzothia-zole-2-thione (BZT) (1), 6-n-propyl-2-thiouracil (PTU) (2), 5-chloro-2-mercap-tobenzothiazole (CMBZT) (3), N-methyl-benzothiazole-2-thione (NMBZT) (4), benzimidazole-2-thione (BZIM) (5), thiazolidine-2-thione (TZD) (6), 2-mercapto-pyridine (PYSH) (7), 2-mercapto-nicotinic acid (MNA) (8), 2-mercapto-benzoic acid (MBA) (9) and 2-mercapto-pyrimidine (PMT) (10) react with producing three type of complexes of formulae [(HL)IJ(l2) (HL= thioamide and n= 0, 1), [(HL) [I3 ] and [(HL-L)]+[l3 ]. The interaction of seleno-amides, derived from, 6-n-propyl-2-thiouracil (RSelJ) (R= Me- (11), Et- (12), n-Pr- (13) and i-Pr- (14)) with I, have also been studied and produced the complexes [(RSeU)IJ of spoke structure. These complexes are stable in non-polar solvents, but they decompose in polar solvents, producing dimeric diselenide compounds or undertake deselenation. 

Oxygen can be transferred from the arene oxides to nitrogen-, sulfur-, or phosphorus-containing substrates like pyridine, thiourea, N-methyl-benzothiazol-2-thione, thioacetamide, thiosemicarbazide, thiols, thio ethers, triphenylphosphine,21,160,161 etc. Parent hydrocarbons are formed as products.162 Thus the dimethoxycarbonyl oxide 269 on heating with pyridine produces 9,10-dimethoxycarbonylphenanthrene (270). The reaction of 1 or its... 

Hydrazino 4 methyl benzothiazole tricyclazole (Sodium boro) hydride imizalil... 

Utilisation of transition metal benzothiazol-2-yMene and especially thiazol-2-ylidene complexes in homogenous catalysis reactions are very rare [42-44], Calo et al. reported the use of bis-(3-methyl-benzothiazol-2-ylidene) palladium diiodide in the Heck reaction of aryl bromides and iodides with a catalyst loading of down to KU mol% and near quantitative yields [42,44],... 

An unsymmetrical cyanine dye for binding to the minor groove of DNA 4-[(3-methyl-6-(6-methyl-benzothiazol-2-yl)-2,3,-dihydro(benzo-l,3-thiaz-ole)-2-methyfidene)]-l-methyl-pyridinium iodide An isotherm for adsorption phenomena in chromatography acronym derived from Stephen Branauer, Paul Emmet, and Edward Teller Bound/free... 

Two fluorimetric techniques have been described, the only essential difference between them being their sensitivity. One method employs vaso-flavine— a sulfonated methylated benzothiazole derivative (B14) which increases linearly in fluorescence in the presence of small amounts of albumin. 

Alkylbenzothiazoles condensate with a,/9-unsaturated ketones or nitriles in dichloromethane-aqueous sodium hydroxyde in the presence of a phase transfer catalyst <87M1 306-03). 2-Methyl-benzothiazole can be efficiently condensed with aromatic aldehydes by using KF- or CSF-AI2O3 base system in dimethylformamide <948973 >. 

Reaction of (2-methyl-5-)- and (2-methyl-6-benzothiazolyl)-dimethyltriazene or 2-methyl-5- and 2-methyl-6-benzothiazolyl-diazonium salts with ferrocene gave 136 (R = ferrocenyl, R = H R = H, R = ferrocenyl, respectivelyUse of the diazonium salts also led to the isolation of some 1,1 disubstituted ferrocenes in this reaction. The compounds 136 were used to prepare thiacyanines. Reaction of ferrocenecarboxaldehyde with the ethiodide of 2-methyl-benzothiazole followed by treatment with potassium iodide gave 137.121... 

M. Ajmal, A.S. Mideen, M.A. Qnraishi, 2-Hydrazino-6-methyl-benzothiazole as an efiective inhibitor for the corrosion of mild steel in acidic solutions, Corros. Sci. 36 (1994) 79—84. 

The literature describes a room-temperature curing epoxide made by converting a part of the epoxy function into episulfide by the addition of NMBTT (N-methyl-benzothiazole-2-thione) (74). 

Then in 1925 Konig used N,2-dimethylbenzothiazolium perchlorate (52) for the preparation of methylene base (53, scheme-15) which was used in the synthesis of thiocyanine dyes (Konig Meier 1925). The quaternary salts of benzothiazoles also found recognition in 1928 by Clark (Clark 1928) while studying the absorption sensitivity of the methylene bases from the quaternary salts of 2-methyl benzothiazole. 

Reactions of Other Derivatives.—Condensation of 2-methyl-benzothiazoles with aromatic aldehydes may be carried out in 50% aqueous sodium hydroxide at room temperature in the presence of triethylbenzylammonium chloride. In some cases the intermediate carbinols are isolable under these conditions. 2-Methylbenzothiazoles undergo the Vilsmeier-Haack reaction to give products [1 R = C( CHOH)CHO] that can be converted into other heterocycles e.g., alkyl- or aryl-hydrazines furnish pyrazoles. ... 

The first empirical and qualitative approach to the electronic structure of thiazole appeared in 1931 in a paper entitled Aspects of the chemistry of the thiazole group (115). In this historical review. Hunter showed the technical importance of the group, especially of the benzothiazole derivatives, and correlated the observed reactivity with the mobility of the electronic system. In 1943, Jensen et al. (116) explained the low value observed for the dipole moment of thiazole (1.64D in benzene) by the small contribution of the polar-limiting structures and thus by an essentially dienic character of the v system of thiazole. The first theoretical calculation of the electronic structure of thiazole. benzothiazole, and their methyl derivatives was performed by Pullman and Metzger using the Huckel method (5, 6, 8). 

Benzothiazole, 3-methyl-N-ethyl-N-(3-cyanoethyl)aniline-4,2 -azo-6 -nitro-visible, 1, 343 <67MI11201)... 

H NMR, 3, 893 (73X2009) 6H-Pyrano[2,3-e]ben20thiazole-8-carboxylic acid, 2-methyl-6-oxo-MS, 3, 615 (70JCS(C)1553) 8ff-Pyrano[3,2-/]benzothiazole 6-carboxylic acid, 2-methyl-8-oxo-MS, 3, 615 <70JCS(C)1553)... 

Benzothiazole, 2-methyl-2-phenyl-2,3-dihydro-synthesis, 6, 325 Benzothiazole, 2-nitro-reactions, 6, 285 Benzothiazole, 5-nitro-nucleophilic attack, 5, 62 reactions... 

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